The malarial fevers, haemoglobinuric fever and the blood protozoa of man . the existence ofan unpigmented quotidian plasmodium, as described by Mannaberg, Manson,and others. Cases of Tertian Aestivo-autumnal Malaria. In the chapters which have preceded this one I have called attention tothe fact that the majority of cases of aestivo-autumnal fever present paroxysmsoccurring, approximately, every 48 hours. These tertian paroxysms arepeculiar in that while they occur every other day, each paroxysm is prolongedso that it lasts considerably over 24 hours, and often almost 48 hours. Thistype of mal


The malarial fevers, haemoglobinuric fever and the blood protozoa of man . the existence ofan unpigmented quotidian plasmodium, as described by Mannaberg, Manson,and others. Cases of Tertian Aestivo-autumnal Malaria. In the chapters which have preceded this one I have called attention tothe fact that the majority of cases of aestivo-autumnal fever present paroxysmsoccurring, approximately, every 48 hours. These tertian paroxysms arepeculiar in that while they occur every other day, each paroxysm is prolongedso that it lasts considerably over 24 hours, and often almost 48 hours. Thistype of malarial fever is further characterized by a peculiar temperature curve,which was first described by Marchiafava and Bignami, and which shows thefollowing characteristics: a rapid and sudden rise, a stage of slight remissions,a pseudocrisis, a precritical rise, during which the temperature generallyreaches a higher point than it had previously, and, lastly, the true crisis, inwhich the temperature rapidly falls to normal or below. 204 THE AESTIVO-AUTUMNAL MALARIAL a THE AESTIVO-AUTUMNAL MALARIAL FEVERS. 205 This peculiar temperature curve is presented in all uncomplicated casesof tertian aestivo-autumnal malaria, where quinine has not been cases infected with two groups of plasmodia sporulating at different timesor by the simple tertian or quartan plasmodium or, again, by both the quotidianand tertian aestivo-autumnal plasmodia, this peculiar temperature curve willnot be observed, nor will it be in cases which have received insufficient doses ofquinine or quinine at long intervals of time. In order, then, to secure a typical temperature chart of tertian aestivo-autumnal fever, we must have a patient infected with a single group of plasmodiaand must withhold quinine for several days. It is safe to say that nearly allof the confusion existing to-day regarding the types of aestivo-autumnalmalaria is due to one or two factors; infection with more than one spec


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