. A text-book upon the pathogenic Bacteria and Protozoa for students of medicine and physicians. Bacteriology; Pathogenic bacteria; Protozoa. The "Lateral-chain Theory" of Immunity 117 by centrifugalization, we investigated whetlier these substances had been taken up by the red corpuscles or remained behind in the fluid. The proof of its loca- tion in the one position or in the other was readily forthcoming, since to restore the hemolysin to its former activity, it was only necessary to add to the ' immune body' a fresh supply of 'complement,' or to the 'complement' a fresh supply of
. A text-book upon the pathogenic Bacteria and Protozoa for students of medicine and physicians. Bacteriology; Pathogenic bacteria; Protozoa. The "Lateral-chain Theory" of Immunity 117 by centrifugalization, we investigated whetlier these substances had been taken up by the red corpuscles or remained behind in the fluid. The proof of its loca- tion in the one position or in the other was readily forthcoming, since to restore the hemolysin to its former activity, it was only necessary to add to the ' immune body' a fresh supply of 'complement,' or to the 'complement' a fresh supply of 'immune body' in order that the presence of the hemolysin in its integrity might be shown by the occurrence of solution of the red cells. The experiments proved that, after centrifugalizing, the 'immune body' is quantitatively bound to the red blood-corpuscles, and that the 'complement,' on the contrary, remains entirely behind in the fluid. The presence of the two components in contact with blood-corpuscles only occasions the solution of these at higher temperatures, and not at o°C. And an active hemolytic serum (with 'immune body' and 'complement' both present) having been placed in contact with red blood- corpuscles and maintained for a while at o°C., it was found after centrifugalizing that, under these circumstances also the 'immune body' had united with the red blood-corpuscles, but that the 'complement' remained in the serum. This experiment showed that both components must, at a tem- perature of o°C., have existed alongside of one another in a free ; .... "But when analogous experiments were undertaken at a higher temperature it was found that both components were retained in the sediment. "These facts can only be explained by making certain assumptions regarding the constitution of the two compo- nents, , of the 'immune body' and the'complement.' In the first place, two haptophore groups must be as- cribed to the 'immune body,' one havi
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectbacteri, bookyear1916