. Diseases of children. pro-portionately larger doses for children. Theamount of thyroid taken daily should be in-creased until the maximum effect is obtained,and then kept at that level until the de-sired improvement has taken, place. Recession of the tongue, loss ofadipose tisue, change in the facial expression, and mental changes arethe first signs of improvement. The skin becomes moist with restora-tion of activity in the sweat glands, the hair grows more abundantly,and is fine and glossy. The body becomes shapely, and there is a rapidincrease in height. The mental improvement is even grea
. Diseases of children. pro-portionately larger doses for children. Theamount of thyroid taken daily should be in-creased until the maximum effect is obtained,and then kept at that level until the de-sired improvement has taken, place. Recession of the tongue, loss ofadipose tisue, change in the facial expression, and mental changes arethe first signs of improvement. The skin becomes moist with restora-tion of activity in the sweat glands, the hair grows more abundantly,and is fine and glossy. The body becomes shapely, and there is a rapidincrease in height. The mental improvement is even greater than thephysical change. These results are usually obtained without increasingthe dose over 15 to 30 grains daily, according to age. Mtev definiteimprovement is noticed the dose may be gradually cut down, and evenstopped at intervals, until the actual amount of thyroid required bythe patient is ascertained. Grafting the thyroid gland has not metwith definite success, and the old method of feeding the fresh gland,33. Fig. 50.—A cretin, twelveyears old. 514 DISEASES OF THE DUCTLESS GLANDS either cooked or uncooked, has been discarded. Overdoses of thethyroid extract may be quite serious, and too large doses cause head-ache, faintness, rapid pulse, nausea, and fever. Exaggerated pulserate is an indication to cut down the dosage. In addition to theadministration of thyroid extract, the child should have the benefitof the best hygienic measures. The diet should be carefully watched,and the protein intake increased. Fresh air is essential, and massageand exercise are of distinct value. DISEASES OF THE ADRENAL GLANDS. The adrenals rarely become diseased before the tenth year, butduring early childhood may be the seat of hemorrhages or into the adrenals may be capillary or punctate. Theyoccur in the newborn, during the course of gastro-enteric infection,chronic cardiac or pulmonary disease, and in septicemia and writers attempt to classify the sympt
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