Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . of Antenatal Pathology and Hygiene. Fisher, Re-ports of the Societv for the Study of Diseases in Children, 1902, vol. ii. 12 Bull, of the Ayer Clinical Laboratory of the Pennsylvania Hospital, Jan.,1905, No. 2, p. 45. VASCULAR SYSTEM. 507 At the present time few doubt the infectious nature of acute endo-carditis. A number of bacteria, mostly micrococci, have been found inthe valves and superimposed vegetation. A])parently the same organ-isms occur in the so-called acute sim])le endoca
Manual of pathology : including bacteriology, the technic of postmortems, and methods of pathologic research . of Antenatal Pathology and Hygiene. Fisher, Re-ports of the Societv for the Study of Diseases in Children, 1902, vol. ii. 12 Bull, of the Ayer Clinical Laboratory of the Pennsylvania Hospital, Jan.,1905, No. 2, p. 45. VASCULAR SYSTEM. 507 At the present time few doubt the infectious nature of acute endo-carditis. A number of bacteria, mostly micrococci, have been found inthe valves and superimposed vegetation. A])parently the same organ-isms occur in the so-called acute sim])le endocarditis and the malignantforms of the afTection. The clinical and anatomic differences betweenthe two classes probably depend upon the pathogenic cajiacity of theorganism or the varying susceptibility of the infected patients. Allforms of acute endocarditis are constantly associated with morbid proc-esses admittedly of microorganismal origin, and an extended study ofthe aflfection. by recent methods, has led to the frequent isolation ofbacteria from the blood during life and from the cardiac lesions post-. Fic. 253. — .\oRTic Orifice Laid , Showing the Valve Leaflets, Acute Endocarditis — {Redrawn from Schnuius.) A. Line of contact with beginning formation of vcKeLiiions. B. More advanced and larger vegetations closelysimulating in appearance an ulcerative lesion. Between the Icatlcl A and the Icatlct imnu-ii,ii< K . tlicletter B is seen a single vegetation on the leaflet B; should a similar lesion occur at theon the leaflet .4, the two, coming together, could coalesce, or the continued deposit ofadjacent masses, and, by organization, would produce an . the two the orifice. mortem. The attempts to establish a specitic organism for endocar-ditis have been unsuccessful. Heiberg and Winge in 1869 demonstrated bacteria in the lesions ofendocarditis. Harblitz analyzed the records upon the subject, andbelieved that it might be possible to d
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