. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 326 OSCAR RIDDLE. TABLE II. SHOWING SOME OF THE KNOWN FACTS OF CHEMICAL EXPERIENCE CONCERNING THE SUCCESSION OF OXIDATIONS OF TYROSIN AND CLOSELY RELATED BODIES TO MELANIN PIGMENTS. Tyrosin = HO- -CH2CH(NH2)_COOH1 Colorless. P-oxyphenyl-pyrotartaric acid= HO—c^ J>—CH2—CO—COOH1 " —CH2—CO— COOH1 >H Hydrochinon-pyrotartaric acid = / \—CH2—CO—COOH1 ". Homogentisic acid4 = ... ( \—CH2— COOH1 " HO ,OH Gentisic acid = N—COOH " HO Melanogen ( ) " Melanin ( ) (White)?2 Melanin ( ) Pale Melanin
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. 326 OSCAR RIDDLE. TABLE II. SHOWING SOME OF THE KNOWN FACTS OF CHEMICAL EXPERIENCE CONCERNING THE SUCCESSION OF OXIDATIONS OF TYROSIN AND CLOSELY RELATED BODIES TO MELANIN PIGMENTS. Tyrosin = HO- -CH2CH(NH2)_COOH1 Colorless. P-oxyphenyl-pyrotartaric acid= HO—c^ J>—CH2—CO—COOH1 " —CH2—CO— COOH1 >H Hydrochinon-pyrotartaric acid = / \—CH2—CO—COOH1 ". Homogentisic acid4 = ... ( \—CH2— COOH1 " HO ,OH Gentisic acid = N—COOH " HO Melanogen ( ) " Melanin ( ) (White)?2 Melanin ( ) Pale Melanin ( ) Deep Melanin ( ) Melanin ( ) Melanin (C50H58Ng SOJ2) Melanin (C45H78N10SO20) (White)?2 and conditions ; these may vary or change from year to year — a power of oxidation not possessed by the individual during many early years of life being attained at manhood, or vice versa. Bateson ('02) has seen fit to claim that (p. 133, note) alkapto- nuria is the result in inheritance of the union of " two ; Garrod has concurred in the view. But in the light of the in- constant and intermittent character of the phenomenon, it seems necessary to draw a directly opposite conclusion. 1 This according to Neubauer ('08). 2 See discussion of Spiegler's work ('03), etc., p. 328 of this paper. 3These from Gessard ('03) and from Bertrand ('08). 4 Concerning the formation of homogentisic acid from tyrosin in plant tissues, see Schulze and Castoro, Zeit. f. Physiol. Chem., Bd. 48, p. 396, Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 1870-1947; Moore, Carl Richard, 1892-; Redfield, Alfred
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