. Diptheria, its nature and treatment . e seen here and therethrough the mass. The lymphatics in the neighborhood con-tain coagula and leucocytes. (See Fig. 7.) Oertel1 in his latest work presents with great minutenessand detail the results of his researches into the histologicalchanges which occur in diphtheria. These consist primarilyand essentially in a characteristic degenerative metamorpho- 1 Die Pathogenese der Epidemischen Diphtheric. Leipzig, 1887. 52 diphthekia; its nature and treatment. sis in the cells and their nuclei. This takes place especially inthe cells which are derived from
. Diptheria, its nature and treatment . e seen here and therethrough the mass. The lymphatics in the neighborhood con-tain coagula and leucocytes. (See Fig. 7.) Oertel1 in his latest work presents with great minutenessand detail the results of his researches into the histologicalchanges which occur in diphtheria. These consist primarilyand essentially in a characteristic degenerative metamorpho- 1 Die Pathogenese der Epidemischen Diphtheric. Leipzig, 1887. 52 diphthekia; its nature and treatment. sis in the cells and their nuclei. This takes place especially inthe cells which are derived from the white blood corpuscles,and are known under the collective name of leucocytes. Thenucleus shows signs of retrogressive metamorphosis. Thenuclear membrane breaks up; the nuclear and the cellularsubstance run into one mass, and the different forms of chro-matin undergo a similar change. The longer this process hascontinued the fewer are the colorable fragments of nucleus,vesicles, granules, etc. The nuclei or granules exhibit peculiar. Fig. 7.—Section of the Uvula in a Case of Diphtheritis Faucium. (The epithelium hasbeen shed ; aniline-brown staining ; X 100) a, micrococci; b, submucous tissue changed intoamorphous blocks ; c, extravasated leucocytes ; d, fibrinous exudation ; e, blood-vessels ; /,lymphatic vessel containing cells and fibrin. forms, as if ligatured and partially divided in two; free nuclearand granular vesicles are seen, and others which are connectedby minute threads. The protoplasm and the nuclei are trans-formed into a homogeneous fluid and finally coagulating sub-stance. Explanation op Figure 8. — Section of a Diphtheritic Pharyngeal Mucous membrane by typical rod-shaped bacteria. Cells in different stages of de-composition and division. Necrosis of these cells and of the upper layers of the mucousmembrane. Advancement of normal cells from the deeper layers, a, necrotic zone; b, diseased zone; c, apparently normal tissue; ,
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Keywords: ., bookcentury1800, bookdecade1880, bookpublishernewyo, bookyear1889
