. The physiology of reproduction. Reproduction. CHANGES IN THE OVARY 145 remaining to form a layer within the outer theca in the fully formed corpus luteum. On the other hand, several investigators have expressed doubts regarding Sohotta's conclusions, and some have adopted the theory originally formulated by von Baer that the luteal cells arise from the connective tissue sheath of the follicle, the folHcular epithelium being either entirely discharged along with the ovum or else being partially discharged and partially de- generating in situ. Amongst those who have adopted this view are Nagel


. The physiology of reproduction. Reproduction. CHANGES IN THE OVARY 145 remaining to form a layer within the outer theca in the fully formed corpus luteum. On the other hand, several investigators have expressed doubts regarding Sohotta's conclusions, and some have adopted the theory originally formulated by von Baer that the luteal cells arise from the connective tissue sheath of the follicle, the folHcular epithelium being either entirely discharged along with the ovum or else being partially discharged and partially de- generating in situ. Amongst those who have adopted this view are Nagel,^ who investigated the human corpus luteum ;. Fig. 34.—Early stage in formation of corpus luteum of mouse. (From Sobotta.) I, developing luteal cells; e, germinal epithelium. Clark,^ who contributed an account of the formation of the corpus luteum in the sow and in the human subject; Doering,' who also worked upon the sow, and claimed to have confirmed Clark's account; and Biihler,* Wendeler,^ ' Nagel, " Die Weiblichen Geschlechtsorgane," Bardeleben's Handbuchder Anatomie des Mensclien, vol. vii., Jena, 1896. " tjber neuere Arbeiten auf dem Gebiete der Anatomie der weiblichen Geschlechtsorgane," Merkel and Bonnet's Ergebnisse d. Anat. u. Entwich, vol. viii, 1899. ^ Clark, "Ursprung, Wachstum, und Ende des Corpus Luteum,'' Arch. f. Anat. u. Phys., Anat. Abth., 1898 ; Johns Hopkins Hospital Reports, vol. vii., 1899. ' Doering, " Beitrag zur Streitfrage tiber die Bildung des Corpus Luteum," Anat. Anz., vol. xvi., 1899. * Biihler, " Entwickelungsstadien Menschlichen Corpora Lutea," Verhand. d. Anat. GeseU., In Pavia, 1900. ' Wendeler, Martin's Die Krankheiten der Eierstocke und Nebeneierstocke. K. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marshall, F. H. A. (


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