Practical pathology; a manual for students and practitioners . Fio. 57.—Acute miliary tubercle of liver. Stained with alum liKmateinand van Giesons stain. ( x 40.) a. Central hepatic vein. b. Portal canal. c. Giant cell tubercle follicle at margin of lobule. d. Tul>ercle follicle without giant cell. Lc. Liver cells in columns between portal capillaries. the centre, or rather running amongst the inner layers of these smallcells, is a network of fibrous tissue, stained pink; in some cases,especially where the nodule is still young, there is very little of thisfibrous tissue. (3) As the centre
Practical pathology; a manual for students and practitioners . Fio. 57.—Acute miliary tubercle of liver. Stained with alum liKmateinand van Giesons stain. ( x 40.) a. Central hepatic vein. b. Portal canal. c. Giant cell tubercle follicle at margin of lobule. d. Tul>ercle follicle without giant cell. Lc. Liver cells in columns between portal capillaries. the centre, or rather running amongst the inner layers of these smallcells, is a network of fibrous tissue, stained pink; in some cases,especially where the nodule is still young, there is very little of thisfibrous tissue. (3) As the centre is neared, the tissue opens out into anetwork with wider spaces, in the meshes of which are found largercells of various shapes. Many of them contain two, three, or evenmore nuclei. These latter appear to be endothelioid cells, such as arefound lying on all bundles of connective tissue, especially where TUBERCLE 281 growth is rapid. (4) The centre of the tubercle is occupied by the giantcell, which is seen as a large branching cell, from the periphery of. * •» t*»?; >? :4jr .^^•t*; re. Flc. 58. — Drawing fiom section of tubercle of the liver. Stainedwith picro-carniine. ( x 300.) ^. Giant cell, with nuclei at the periphery, and sending oftbranching processes. Endothelioid cells, lying on fibrilku of the network of connec-tive tissue, with which the branching processes of the giantcell appear to anastomose. ;?.(•. Round cells, young connective tissue corpuscles, and leucocytesappearing towards the periphery of the mass. /./. Fibrous tissue, forming a kind of capsule to the tubercle. Inthis capsule are a number of rounded nuclei. /.r. Columns of liver cells, those near the tubercle somewhatflattened and atrophied ; between them are rounded nuclei,etc., extending from the growing tubercle mass. /i.(f. Small bile duct. a. Branch of hepatic artery. which processes run to join the fibrous reticulum ; in the liver theseprocesses can often be very distinctly seen.
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