. The physiology of reproduction. Reproduction. 422 THE PHYSIOLOGY OF REPRODUCTION bi-lobed (Fig. 101). The folds of the mucosa are essentially increased areas of the mucosal connective tissue, but they differ from the cotyledons of Ruminants in having glands. On the entrance of a fertilised ovum into the uterus, the folds, especially the ob-placental, become shortened, and a locahsed actual cavity appears which is occupied by the blasto- cyst. At the same time there is a marked hyperplasia of the cellular connective tissue of the placental and peri-placental folds, leading to a thickening of
. The physiology of reproduction. Reproduction. 422 THE PHYSIOLOGY OF REPRODUCTION bi-lobed (Fig. 101). The folds of the mucosa are essentially increased areas of the mucosal connective tissue, but they differ from the cotyledons of Ruminants in having glands. On the entrance of a fertilised ovum into the uterus, the folds, especially the ob-placental, become shortened, and a locahsed actual cavity appears which is occupied by the blasto- cyst. At the same time there is a marked hyperplasia of the cellular connective tissue of the placental and peri-placental folds, leading to a thickening of their bases (Chipman ^). By the. Fig. 101.—Transverse section of a seven days' gestation sac of the rabbit (Chipman). The placental folds {coussinets) are large (a); the muscular walls of the sac are thin. sixth day, the capillaries are also increased in these regions. In the ob-placental folds appear enormous giant-cells, derived by a process of " degenerative hypertrophy" from the epithehum of the surface and glands. They persist till the fourteenth day, and are probably absorbed by the trophoblast overlying the yolk-sac. In the placental lobes the epithehal 1 Chipman, " Observations on the Placenta of the Rabbit, with Special Reference to the Presence of Glycogen, Fat and Iron," Laboratory Reports, Roy. Coll. Phys., Edinburgh, vol. viii., 1903. The development of the placenta is carefully traced in a complete age-series of pregnant rabbits and admirably figured by many photo-micrographs. The account as given here is based mainly on Chipman's monograph, but the phraseology is some- times Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marshall, F. H. A. (Francis Hugh Adam), 1878-1949; Cramer, William, 1878-1945; Lochhead, James. London, New York, Longmans, Green
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