. Adventures in radioisotope research;. Radioactive tracers; Radiobiology. 428 ADVENTURES IN RADIOISOTOPE RESEARCH jected to that found after a given time is also stated. Furthermore, the diluting volume is expressed in percent of the rabbit's body weight. We shall first compare the rate of disappearance of sodium, chlorine, and bromine from the circulation. This comparison encounters no difficulties since practically the sole outlet of these elements from the circulation is the extracellular body fluid, though some ^^Na is taken up by the bone apatite (Hahn et ah 1939). No great diffe-. FiG.
. Adventures in radioisotope research;. Radioactive tracers; Radiobiology. 428 ADVENTURES IN RADIOISOTOPE RESEARCH jected to that found after a given time is also stated. Furthermore, the diluting volume is expressed in percent of the rabbit's body weight. We shall first compare the rate of disappearance of sodium, chlorine, and bromine from the circulation. This comparison encounters no difficulties since practically the sole outlet of these elements from the circulation is the extracellular body fluid, though some ^^Na is taken up by the bone apatite (Hahn et ah 1939). No great diffe-. FiG. 2. Rate of disappearance of various labelled ions from the plasma. rence is found between the rate of passage of sodium, chlorine, and bromine through the capillary wall but the values obtained for dif- ferent rabbits show fairly large variations. These variations are to some extent due to differences in the size of the extracellular space. A comparison of the rate of passage of potassium, phosphate, and water with that of sodium, chlorine, and bromine encounters some difficulties since potassium, and the same applies to phosphate and water, has an additional outlet into the tissue cells in contrast to the first mentioned group. The amount of ^-K lost by the blood after the lapse of a given time is the resultant of the amount penetrated into the tissue fluids and that returned from the latter into the blood. When 1 In experiments taking up to 1 hour, the amount of ^^Na lost by excretion is less than 1 per cent of the amount Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Hevesy, Georg von, 1885-1966. New York, Pergamon Press
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