The practice of pediatrics . Positive Widal reaction, showing agglutination of typhoid fever bacilli—with blood fromtyphoid patient—at end of thirty minutes. in water that is contaminated by sewage. Other foods may becomeinfected, particularly those which are eaten raw and previously washedin infected water. Predisposing Factors.—Sex appears to have no influence on theoccurrence of the disease. Season.—Typhoid fever is endemic in most localities. It occurs atall seasons of the year, although it is commonly stated that it is mostprevalent in the fall months. Osier says typhoid is essentially an
The practice of pediatrics . Positive Widal reaction, showing agglutination of typhoid fever bacilli—with blood fromtyphoid patient—at end of thirty minutes. in water that is contaminated by sewage. Other foods may becomeinfected, particularly those which are eaten raw and previously washedin infected water. Predisposing Factors.—Sex appears to have no influence on theoccurrence of the disease. Season.—Typhoid fever is endemic in most localities. It occurs atall seasons of the year, although it is commonly stated that it is mostprevalent in the fall months. Osier says typhoid is essentially anautumnal fever, and more than one-half of his cases were admitted inAugust, September, and October. Frequency in Children.—From 200 cases of my own which wereobserved for the most part in the Michael Reese Hospital, Chicago,the following tabulation of ages is made: PLATE Typhoid Ulceration of the Ileum. (From the Laboratory of the College of Physicians and Surgeons, Columbia University, NewYork. Photograph by D . Edward Learning.) TYPHOID FEVER 429 0 to 1 year 2 6 : 1 to 2 years 2 7 2 . 7 8 to 14 4 . 18 5 . 16 years .... 14 12 . 129 200 Pathology.—The opinion is general that typhoid fever in infantsproduces less pronounced anatomical changes than in older childrenand adults. In some cases, however, autopsies on comparatively youngchildren have shown anatomical changes not dissimilar to those whichoccur in adults. As a result of the typhoid infection, hyperplasticprocesses in the intestine are more pronounced than the ulcerativeones. The typhoid bacillus in the small intestine produces swellingof the solitary follicles and Peyers patches. These appear raised,of a rose-red color, and surrounded by a circumscribed area of red-ness. The process does not remain localized in the intestine. Recentinvestigations, particularly the bacteriologic studies of
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Keywords: ., bookcentury1900, bookdecade1900, booksubjectchildren, bookyear190
