. The elements of pathological histology with special reference to practical methods . ary, completely caseous nodules, only surrounded at their peri-phery by a narrow zone of granulation tissue, which, however,may still enclose typical epithelioid-celled or giant-celled the inner meninges of the brain and cord, tuberculosis (Fig. 172)gives rise to the formation of minute nodules, mostly in largenumbers, which usually lie in the immediate neighbourhood ofthe blood-vessels {a and h). The latter also are soon implicated TUBERCULOSIS AND SYPHILIS 347 in the process, either by the ext


. The elements of pathological histology with special reference to practical methods . ary, completely caseous nodules, only surrounded at their peri-phery by a narrow zone of granulation tissue, which, however,may still enclose typical epithelioid-celled or giant-celled the inner meninges of the brain and cord, tuberculosis (Fig. 172)gives rise to the formation of minute nodules, mostly in largenumbers, which usually lie in the immediate neighbourhood ofthe blood-vessels {a and h). The latter also are soon implicated TUBERCULOSIS AND SYPHILIS 347 in the process, either by the extension to their walls of thecaseation occurring in the tubercles (r?), or by the vessel itselfbecoming the seat of a pronounced tubercular vasculitis, in whichits wall is at first infiltrated, and its lumen filled, with roundand epithelioid cells, whilst later the entire tubercular new-forma-tion caseates (Fig. 107). The development of tubercles is veryoften associated with an inflammatory exudation (Fig. 172, e) in thecerebro-spinal membranes, and at tlie same time the process may. Fig. 172.—Tubercular Leptomeningitis affecting the Optic , togetherWITH Neuritis, x 95. (Hsematoxylin and eosin.) A, Internal meninges; B, Opticnerve ; a, Caseous tubercle surrounding a partially caseous vessel in the form of a ring ;h. Partially caseous tubercle; c, Artery in ti-ansverse section, with partially caseatedwalls; cZ, Caseous infiltration formed by the coalescence of tubercles; e, Fibrinousexudation; /, Perineurium ; r/, Blood-vessels of the endoneurium surrounded withsmall-celled inliltration ; /i, Interstitial connective-tissue of the nerve, with small-celledi)ifiltration. also extend along the vessels into the actual substance of the brainand cord, where it either restricts itself to the vessel-sheaths, orattacks the actual nervous substance. Syphilis occurs not only in the brain and spinal cord themselves,but in the meninges and the nerves issuing from them, taking onthe o


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Keywords: ., bookcentury1800, bookdecade1890, booksubjectpatholo, bookyear1895