The Journal of laboratory and clinical medicine . toi y of PatholoKy of the Iliivcisity nf Cincinnati, anil tlieIatholdgic Institute of the Cincinnati General Hospital. 348 The Journal of Laboratory and Clinical Medicine 2. In a certain group of cases there are anomalies of the iicart, of thevessels, or of the uropoietic system of the fetus. 3. In a certain group of cases the edema of the fetus seems to be as-sociated with maternal disease—chiefly nephritis. 4. In another group none of the above mentioned factors are present, andin this it has been supposed that some metabolic anomaly of the f
The Journal of laboratory and clinical medicine . toi y of PatholoKy of the Iliivcisity nf Cincinnati, anil tlieIatholdgic Institute of the Cincinnati General Hospital. 348 The Journal of Laboratory and Clinical Medicine 2. In a certain group of cases there are anomalies of the iicart, of thevessels, or of the uropoietic system of the fetus. 3. In a certain group of cases the edema of the fetus seems to be as-sociated with maternal disease—chiefly nephritis. 4. In another group none of the above mentioned factors are present, andin this it has been supposed that some metabolic anomaly of the fetus developswhich finds expression in abnormal blood production and edema. It is this last group which is most interesting, for in it belong the casesof what has been called fetal erythroblastosis (Raubmann). This very peculiarand almost generally unrecognized complex is characterized, as Schridde said,by the following features: I. The fetuses (premature as a rule) show universal edema in the formof anasarca, and hydrops of the body rig. 1.—A low power photoinicrograph of a liver section to show the islands of (chiefly) erythroblasts and the atrophy of the hepatic parenchyma. 2. Most of them show also edema of the placenta and cord. 3. The liver and spleen are markedly enlarged. 4. Microscopic examination of the liver and spleen show unusually largenumbers of erythroblasts with large numbers of other myeloid cells, inside andoutside the vessels. Also, the liver cells are atrophic, and in the spleen thefollicles are absent. In other organs, especially in the kidneys and lymph nodesextramedullary erythroblastic nodules appear, and the blood shows enormousnumbers of erythroblasts overshadowing all other elements. Mitotic and rhec-tic figures appear, and the liver cells and pulp cells of the spleen are coloredwith iron-containing pigment. These characters were shown in their entirety by a case sent me by Iv. Woodward, which, however, was more than usually inte
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Keywords: ., bookcentury1900, bookdecade1910, booksubject, booksubjectmedicine
