. The American journal of roentgenology, radium therapy and nuclear medicine . areaof hyperemia. Magnification, x6o. (For furtherreference see text.) dium emanation. It was placed under thescalp in the right cerebral region, and leftthere for 30 days. The scalp immediatelyabove the tube was destroyed over an area of8 by 10 mm. The brain lesion showed a cen-tral necrotic area, 4 by 5 mm. in diameter,which was sharply demarcated by a broadzone of polynuclear leukocytes, beyondwhich was a wide area of hyperemia andsome pial-edema. The ganglian cells near thenecrotic zone showed marked hydropic de
. The American journal of roentgenology, radium therapy and nuclear medicine . areaof hyperemia. Magnification, x6o. (For furtherreference see text.) dium emanation. It was placed under thescalp in the right cerebral region, and leftthere for 30 days. The scalp immediatelyabove the tube was destroyed over an area of8 by 10 mm. The brain lesion showed a cen-tral necrotic area, 4 by 5 mm. in diameter,which was sharply demarcated by a broadzone of polynuclear leukocytes, beyondwhich was a wide area of hyperemia andsome pial-edema. The ganglian cells near thenecrotic zone showed marked hydropic de-generation, and all the nuclei stained of the cells were completely broken up, 540 The Action of Buried Tubes of Radium Emanation there were minute blood extravasations withsome increase in the small compact nuclei inthis area, and the neighboring pia showedmarked round-cell infiltration. The cellsof the adjoining convolutions showed chro-matic bodies that did not stain well. Therewere pericellular and perivascular cerebellum appeared normal, but the. Plate V. Low Power Photograph of a NormalRats Brain, selected to show the marked leu-kocytic infiltration, tending to localize the effectsof the radiation. A glass tube containing was placed between the calvarium andscalp, and left in place for 30 days. Magnifica-tion, (For further reference see text.) chromatic bodies and Purkinji cells did notstain well. Plate IV shows a high power viewof the periphery of the lesion, which extendsbeyond the mid-line of the brain. Series B. Buried Radium EmanationTubes in Flexner-Johling Rat of the rapidity with which the tu-mor cells respond to treatment, it was foundmore difficult to determine the area of ra-diated tissue about the radium tube in agrowing tumor than in normal tissues. In some cases the tumor was promptly reducedin size, but again, attending inflammationand edema may be considerable, and al-though the actual amount of
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