. Senescence and rejuvenescence. Age; Reproduction. 294 SENESCENCE AND REJUVENESCENCE occur in such cases and that the regeneration takes its origin from cells or parts of cells which have never undergone differentiation, so that even in these cases development is progressive, not regres- sive. His conclusions are based on the histological appearance, not upon the behavior of the cells. One of the cases cited by him as an example is the regeneration of striated muscle after injury. He points out that the only portions of the muscle which take part in the regeneration are the nuclei and the sma
. Senescence and rejuvenescence. Age; Reproduction. 294 SENESCENCE AND REJUVENESCENCE occur in such cases and that the regeneration takes its origin from cells or parts of cells which have never undergone differentiation, so that even in these cases development is progressive, not regres- sive. His conclusions are based on the histological appearance, not upon the behavior of the cells. One of the cases cited by him as an example is the regeneration of striated muscle after injury. He points out that the only portions of the muscle which take part in the regeneration are the nuclei and the small accumulations of. Figs, i 17-122.—Various stages of regeneration after wounding in striated muscle: Fig. 117, injured muscle after three days, showing proliferation of nuclei and formation of protoplasmic cells; Fig. 118, multinucleate masses resulting from proliferation; Figs. 119, 120, "muscle buds" at ends of injured fibers; Fig. 121, regenerated fibers; Fig. 122, giant cells, inclosing a piece of necrotic muscle fiber. From Ziegler, '01. granular undifferentiated cytoplasm, as he terms it, which surround them. From these parts the new muscle cells arise by division of the nuclei and growth of the granular cytoplasm (Fig. 117); these cells form multinucleate masses either along the course (Fig. 118) or at the injured end of the fibrillar substance (Fig. 119). From the cytoplasm of these cells new fibrillar substance arises in con- tinuity with the old (Figs. 120, 121). When these cells are not in contact with living muscle substance, as at b in Fig. 117, they form. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Child, Charles Manning, 1869-1954. Chicago, Ill. , The University of Chicago Press
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