. University of Toronto studies. Physiological series. no. 1-98. 1900-28 . ne in the fowl. ( kgm.)Produced by cc, 1:10,000 adrenalin. (Reduced %). seven animals no evidence of the existence of theadrenalin vasodilator mechanisms (Table 1) has beenfound. TABLE TO ADRENALIN IN THE FOWL Blood pressure Weight Dose change in mm. Limb Intestine in kgm. of mercury cc 1:1,000,000 Slight con-striction cc 1:100,000 109-138 Constriction cc 114-182 Marked con-striction cc 1:100,000 118-130 Constriction cc 106-134 Marked con-striction cc 65- 79 Constr
. University of Toronto studies. Physiological series. no. 1-98. 1900-28 . ne in the fowl. ( kgm.)Produced by cc, 1:10,000 adrenalin. (Reduced %). seven animals no evidence of the existence of theadrenalin vasodilator mechanisms (Table 1) has beenfound. TABLE TO ADRENALIN IN THE FOWL Blood pressure Weight Dose change in mm. Limb Intestine in kgm. of mercury cc 1:1,000,000 Slight con-striction cc 1:100,000 109-138 Constriction cc 114-182 Marked con-striction cc 1:100,000 118-130 Constriction cc 106-134 Marked con-striction cc 65- 79 Constriction Constriction cc 95-175 Marked con-striction cc 1:1,000,000 52- 54 Constriction cc 1:100,000 55- 65 Marked con-striction Constriction cc 80-119 Constriction cc 1:100,000 Constriction cc 1:10,000 Very markedconstriction MAMMALIAMarsupialia (Didelphys)A single opossum about two-thirds grown ( kgm.) was used in this research. A fall in blood HARTMAN, KILBORN AND LANG 127 Dressure (Fi^. 3) was easily obtained from adrenalii:.. FIG. 3Blood pressure fall in the opossum produced by ,1:100,000 adrenalin. (Reduced %.) This was usually preceded by a brief rise. Withlarger doses pure pressor effects resulted. Although the limb included in the plethysmographpossessed a smaller proportion of muscle than that inmost mammals it gave active dilatation (Fig. 4) ex-
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