. The endocrine organs; an introduction to the study of internal secretion . ndary sexual organs—especially theprostate and seminal vesicles—remain in an undeveloped condition, and thespecial secondary sexual characters, such as the growth of hair on the face,the enlargement of the larynx, and the development of the male characters 134 The Endocrine Organs of the skeleton, are not seen. In such animals as birds and deer, in whichthe external characteristics of the male sex are well marked, thesecharacteristics fail to show themselves, the general features of developmentapproaching those usual
. The endocrine organs; an introduction to the study of internal secretion . ndary sexual organs—especially theprostate and seminal vesicles—remain in an undeveloped condition, and thespecial secondary sexual characters, such as the growth of hair on the face,the enlargement of the larynx, and the development of the male characters 134 The Endocrine Organs of the skeleton, are not seen. In such animals as birds and deer, in whichthe external characteristics of the male sex are well marked, thesecharacteristics fail to show themselves, the general features of developmentapproaching those usual to the female sex. In the skeleton, the epiphyseslong remain separate; the limb bones are longer and more delicate thanusual, and the sutures of the skull slower in ossifying. The mental char-acter also tends to retain a more infantile type. Most of the ductlessglands are in some way affected, the growth of the thyroid beingdiminished, that of the suprarenal cortex, pituitary, and thymus increased :the last-named organ shows arrest of its normal retrogressive ;*^ -A v. w**^S*« ^ *-»>*; *^ &fc **=^ . ,^-i, 3p «? •; ^ _i fe » . < r-- i ^«3-m TO. GBt™^ *-L w FIG. 92.—Interstitial cells of testicle, cat. Magnified 200 diameters. Parts of threetubules are included in the photograph. If castration is performed in the mature animal, and therefore after thesecondary sexual characters have become developed, there may be someretrogression of these, and such accessory generative glands as the prostatetend to undergo atrophic changes. But the effects are now mainly uponmetabolism, and are shown in a tendency to increased formation of fat,although the limit of assimilation of carbohydrates is lowered and alimentaryglycosuria is more easily produced. How far these effects on metabolismare direct or how far indirect, through other endocrine organs, it is not pos-sible to say, but the fact seems to be well established that the pituitary bodybecomes hypertroph
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