The pathology and surgical treatment of tumors . Fig. 380.—Spindle-cells from sarcoma (after Liicke). 381). The cells vary greatly in size and shape, but a certain uniformityis observed in each tumor. The shape of the cell is not only greatlyinfluenced by the structure of the mesoblastic tissue in which the tumororiginates, but also by the cell-environments. The cells are oftenmoulded into different shapes by pressure. The shape of the nucleusis determined by the shape of the cell. The nucleus is always clear,well-defined, and surrounded by a proper nuclear membrane. The con-tents of the nucle
The pathology and surgical treatment of tumors . Fig. 380.—Spindle-cells from sarcoma (after Liicke). 381). The cells vary greatly in size and shape, but a certain uniformityis observed in each tumor. The shape of the cell is not only greatlyinfluenced by the structure of the mesoblastic tissue in which the tumororiginates, but also by the cell-environments. The cells are oftenmoulded into different shapes by pressure. The shape of the nucleusis determined by the shape of the cell. The nucleus is always clear,well-defined, and surrounded by a proper nuclear membrane. The con-tents of the nucleus vary according to the age of the cell. In youngand rapid-growing sarcoma the contents are rich in chromatin; laterthe chromatin is diminished and there appears a beautiful network ofchromatin threads that do not readily absorb staining material. One ortwo nucleoli which are deeply stained are always present. In young 534 PATHOLOGY AND TREATMENT OF Fig. 381.—Giant-cells from sarcoma (afterLiicke). tumors, besides cells, leucocytes are always present, but their numberis usually limited. They are most numerous along the course of blood-vessels. Although the imperfect condition of the capillary walls would appear to favor emigration of leuco-cytes, the escape of leucocytes is are found in abundance onlyin young and rapid-growing tumors. Ina specimen examined by Klebs he foundthe large vessels of the tumor partlyclosed by normal white thrombi. Theexistence of the leucocytes in the tumoris of short duration. Sarcoma-cells reproduce themselvesby karyokinesis, as was first observedand described by Van Henkelem. Thesame method of cell-reproduction insarcoma has been studied by Aryamaand Klebs. Distinct alveolation of thestroma of sarcoma is observed only inexceptional in 1869 introduced the term alveolar sarcoma, and includedin this variety of sarcoma all tumors in which the connective-tissuestroma sh
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Keywords: ., bookcentury1800, bookdecade1890, booksubjectneoplas, bookyear1895
