. The bacteriology of the eye. erful resistance to the infection, and in such cases wefind pneumococcal infection taking on the form of a simple infiltrate, without anydense progressive border. 304 BACTERIOLOGY OF THE EYE Augstein confirms this, and states that an ulcus serpens with Pneumococci isvery rare in trachoma, even in cases with dacryocystitis, although in these patientsepithelial defects, both traumatic and spontaneous, frequently occur. Augsteinconsiders this as proof that trachoma, or rather its causal agent, must have a directantagonism to the Pneumococeiis. His view is not based
. The bacteriology of the eye. erful resistance to the infection, and in such cases wefind pneumococcal infection taking on the form of a simple infiltrate, without anydense progressive border. 304 BACTERIOLOGY OF THE EYE Augstein confirms this, and states that an ulcus serpens with Pneumococci isvery rare in trachoma, even in cases with dacryocystitis, although in these patientsepithelial defects, both traumatic and spontaneous, frequently occur. Augsteinconsiders this as proof that trachoma, or rather its causal agent, must have a directantagonism to the Pneumococeiis. His view is not based on adequate , then, is the relation between the Pneumococci in the sac and on the con-junctiva and the trachomatous process ? The irregular epidemiological distributionof the affection shows that other factors may possibly be the cause of the infre-quency in Egypt of pueumoeoccal conjunctivitis compared to other forms ofinfection. In Italy Gasparrini and others have shown that it is very often \ J J . * ■ Y<C:. 1 ig. 65.—Uhthoff and Axenfeld : Pneumococci from Ulceea in Form. 1, Pus from the infiltrate in a rabbits cornea after inoculation, showing phagocytes andinvolution forms ; 2, agar culture (pure) from an ulcus serpens—(a) typical Diph(b) involution forms with short chains, (c) pronounced bacillary t}Tpe ; 3, chain-formation in a bouillon culture ; 4, unusual formation of capsules and chains in agar,type resembling the Streptococcus mucosus. a complication of granular ophthalmia. And it is quite possible that vascularityof a pannus and cellular infiltration of the cornea may prevent such infections, andperhaps render them innocuous before they have been able to produce the disi In scrofulous persons with vascularized cornea, as I have twice been able to show, apneumococcal infection can produce the appearance of a keratitis fasciculosa—a snail-track ulcer. This peculiar form of keratitis in scrofula is similar to ulcus serpensin
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