. Ciba Foundation Symposium on the Regulation of Cell Metabolism. Cell metabolism. Discussion 187 The basis of the calculation is that it comes off equally from the two in the glycolytic pathway. Of course, there are many difficulties in this. The interpretation of our results is straightforward, based on the yields from glucose labelled in positions 1 and 6. King: The limiting factor may not be the obvious one expected; for instance, the rates of the reactions in the glycolytic pathway may be quite different from those in the pentose phosphate cycle. If so, will it affect the calculation or i
. Ciba Foundation Symposium on the Regulation of Cell Metabolism. Cell metabolism. Discussion 187 The basis of the calculation is that it comes off equally from the two in the glycolytic pathway. Of course, there are many difficulties in this. The interpretation of our results is straightforward, based on the yields from glucose labelled in positions 1 and 6. King: The limiting factor may not be the obvious one expected; for instance, the rates of the reactions in the glycolytic pathway may be quite different from those in the pentose phosphate cycle. If so, will it affect the calculation or interpretation? Dickens: It is unlikely that in the glycolytic-citric acid pathway it would be at the same rate, because it goes through a whole chain of about 30 reactions before it is entirely liberated, and many of these may involve dilution of i*C, whereas in the pentose pathway it comes off in the first step as ^^COg Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Ciba Foundation Symposium on the Regulation of Cell Metabolism (1958 : London, England); Wolstenholme, G. E. W. (Gordon Ethelbert Ward); O'Connor, Cecilia M. (Cecilia Mary), 1927-. Boston, Little, Brown
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