. Annual of the universal medical sciences. Fig. 6. ASY3IMETKICAI. CONDITIONS .MKT WITH IN THE FACES OF THE INSANE. (Journal of Mental /Science.) D-16 ROHE. r Insanity. J. Ramadier and P. Serieux g^pt^ol-gi (describe a peculiar mal-formation of the chest, illustrated in the accompanying- plates,and known, after Ebstein, as funnel-breast {Trichterhrust—TJiorax en entonnoir). Eleven cases are collected from theliterature and five new cases reported. The authors claimtliat funnel-breast is one sign of physical degeneration. Inten of the reported cases there were hereditary psychopathic con-dition


. Annual of the universal medical sciences. Fig. 6. ASY3IMETKICAI. CONDITIONS .MKT WITH IN THE FACES OF THE INSANE. (Journal of Mental /Science.) D-16 ROHE. r Insanity. J. Ramadier and P. Serieux g^pt^ol-gi (describe a peculiar mal-formation of the chest, illustrated in the accompanying- plates,and known, after Ebstein, as funnel-breast {Trichterhrust—TJiorax en entonnoir). Eleven cases are collected from theliterature and five new cases reported. The authors claimtliat funnel-breast is one sign of physical degeneration. Inten of the reported cases there were hereditary psychopathic con-ditions (idiocy, epilepsy, imbecility, delusional insanity). Inonly one of the cases was there slight scoliosis. No evidence ofrachitis. In the other cases the history was incomplete. In oneof the cases there was also malformation of the index finger ofeach hand (see illustration). The alterations found in the pia mater in various forms ofinsanity are thus described by ;ju?,7 1- Ii^ general. Malformations of the Index Fingers.(JVouvellc Iconographie de la Salpetriere.) paralysis we find peri-arteritis of tlie smallest vessels of the pia,especially in the layer nearest the cortex; in general, the signs ofchronic fibrous leptomeningitis. At times, in the smallest vesselsof this region, besides peri-arteritis, we find obliterating endo-arteritis, and, in the medium-sized vessels, thickening and fattydegeneration of the muscular coat. 2. The regularity with whichwe find peri-arteritis of the smallest vessels in general paralysis,even in patients who die early, when the brain-substance shows nosign of sclerosis or atrophy, goes to support the vicAvs of Meyer,Kumpf, and Mendel, that the vascular lesions, as a result of per-sistent hyperasmia, represent the first histological changes in thebrain of the general paralytic, and that the changes in the cells andneuroglia are secondary. 3. In pellagrous insanity we find thepia diffusely opaque, with slight increase of connective tis


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