A practical treatise on urinary and renal diseases : including urinary deposits . 7. 378 ACUTE BRIGHTS DISEASE. chocolate sediment, like the settling from beef-tea. It is veryalbuminous ; it may even become quite solid on boiling. Thespecific gravity, in the stage of increment, is usually above1020, often much higher, mounting sometimes to 1030, and inone instance which occurred to me even to 1065. When ofhigh density, the urine is proportionally scanty ; it may notexceed 12 or 18 ounces in the twenty-four hours ; in extremecases it may sink to 4 or 6 ounces, or be, for two or three days,altog
A practical treatise on urinary and renal diseases : including urinary deposits . 7. 378 ACUTE BRIGHTS DISEASE. chocolate sediment, like the settling from beef-tea. It is veryalbuminous ; it may even become quite solid on boiling. Thespecific gravity, in the stage of increment, is usually above1020, often much higher, mounting sometimes to 1030, and inone instance which occurred to me even to 1065. When ofhigh density, the urine is proportionally scanty ; it may notexceed 12 or 18 ounces in the twenty-four hours ; in extremecases it may sink to 4 or 6 ounces, or be, for two or three days,altogether suppressed. The calls to void it are more frequentthan in health, especially at night and in the recumbentposture ; the patient has to get up three or four times in thecourse of the night to empty the bladder. The urine is gene-rally acid, and surcharged with pigment; it often deposits theamorphous urates. Very rarely it is alkaline from fixed natural urinous odour is lost; it has a faint unpleasantsmell which has been compared to that of the washings N OS SV m] Fig. 52.—Transparent, granular, blood and epithelial casts from a case of acuteBrights disease ; free renal epithelium : and blood disks. The deposit when examined microscopically (see Fig. 52) isfound to consist of blood-corpuscles, loose renal epithelium, COURSE AND SYMPTOMS. 379 free nuclei of these, tube-casts, shapeless masses of coagulatedfibrine, and the broken debris of all these structures. There are also generally found epithelial cells from the pelvisof the kidney and the bladder. The renal epithelia vary a good deal in their they look almost natural, only somewhat swollenand opaque. More frequently they are much broken down ;their nuclei are set free, or are only invested in part by thegranular cell-contents which naturally surround them. Thedisintegrated epithelium forms an amorphous dark granulardebris scattered over the field. When very abundant, theepithe
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