. Pathology and bacteriology [electronic resource]. Ophthalmology; Eye; Eye; Bacteriology; Ophthalmology; Eye; Bacteriology; Eye. 670 DEGENERATIONS pate, their coats becoming thickened and their lumen narrowed. In some diseases, such as syphihs, either pri- mary or secondary sclerosis may occur. Thus during the secondary stage, when the syphilitic infection is general, it causes a widespread endarteritis followed by primary vascular sclerosis; but when the disease is localised, as in disseminated choroiditis, it causes an intense local secondary vascular Fig. 292.—Shows a section t
. Pathology and bacteriology [electronic resource]. Ophthalmology; Eye; Eye; Bacteriology; Ophthalmology; Eye; Bacteriology; Eye. 670 DEGENERATIONS pate, their coats becoming thickened and their lumen narrowed. In some diseases, such as syphihs, either pri- mary or secondary sclerosis may occur. Thus during the secondary stage, when the syphilitic infection is general, it causes a widespread endarteritis followed by primary vascular sclerosis; but when the disease is localised, as in disseminated choroiditis, it causes an intense local secondary vascular Fig. 292.—Shows a section through the retina, with a sclerosed artery cut trans- versely. Note the thickening of the vessel's coats. The effect of vascular sclerosis is to lessen the lumen of the vessel, and so to inhibit the nutrition of the part by diminishing or completely cutting off the blood supply to it. If the constriction of the vessels is general throughout the system the blood pressure is raised, and this, together with the disease in the capillaries, produces changes in the walls of the latter which allows of a transudation of their contents (see page 280). The secondary effects of vascular sclerosis have already been described (vsee pages 471 and 476). The actual change found in the larger vessels when sclerosed is an increase of the connective and elastic tissue in their walls (Fig. 292). This is .especially marked in the. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Collins, E. Treacher (Edward Treacher), 1862-1937; Mayou, M. Stephen (Marmaduke Stephen), 1876-1934; Pyle, Walter L. (Walter Lytle), 1871-1921, editor; University College, London. Library Services. London : William Heinemann
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