. Electrolytes in biological systems, incorporating papers presented at a symposium at the Marine Biological Laboratory in Woods Hole, Massachusetts, on September 8, 1954 . Fig. 4. K influx into dog red cells is plotted as a function of K concentration in the medium ([K™]). kg H2O, their mean values. These values for D'k in dog cells are not too dif- ferent from the values of . obtained for human cells. The apparent activation energy for K influx in dog cells is 12,000 cal/mole. Measurements of Na transport in dog cells (95) do not include the eff'ect of variations of [Na],„ in Na infl
. Electrolytes in biological systems, incorporating papers presented at a symposium at the Marine Biological Laboratory in Woods Hole, Massachusetts, on September 8, 1954 . Fig. 4. K influx into dog red cells is plotted as a function of K concentration in the medium ([K™]). kg H2O, their mean values. These values for D'k in dog cells are not too dif- ferent from the values of . obtained for human cells. The apparent activation energy for K influx in dog cells is 12,000 cal/mole. Measurements of Na transport in dog cells (95) do not include the eff'ect of variations of [Na],„ in Na influx. However, inspection of the rate constants shown in table i shows that the ratio of the inward to outward rate constant for Na transport closely approximates that predicted for diffusion. The value of D'xa = 'kNa = .093 is considerably higher than the value of .021 obtained for human red cells at 37°C. Thus, K and Na transport in dog red cells can, in large part, be accounted for according to diffusion theory. Furthermore, the effective diffusion coef- ficient for K in the dog cell membrane is not appreciably greater than in the human cell membrane. The main difference in the cation transport apparatus of the two cell types appears to be the presence of a system of chemical reac-
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