. Transactions. ect. Y : R. |g f^ 2, 1 J., at ir fluently. L. |^5 |§2,1 J., at 12 fairly. Slight paresis of 1. internal sign of syphilis expect slight enlargement of posteriorcervical glands. The fields practically the same as inMarch, except that the space at outer periphery haddecreased. 0. pale, vessels remarkably small andcontracted. No other change in fundus. From that time to December 4th, scarcely any changehas taken place, except slight failure in Y. of L. Y. : ^6, L. f§4. When reading 1 J. with L. eye, the lettersdance : this is, I presume, due to the slight weakness


. Transactions. ect. Y : R. |g f^ 2, 1 J., at ir fluently. L. |^5 |§2,1 J., at 12 fairly. Slight paresis of 1. internal sign of syphilis expect slight enlargement of posteriorcervical glands. The fields practically the same as inMarch, except that the space at outer periphery haddecreased. 0. pale, vessels remarkably small andcontracted. No other change in fundus. From that time to December 4th, scarcely any changehas taken place, except slight failure in Y. of L. Y. : ^6, L. f§4. When reading 1 J. with L. eye, the lettersdance : this is, I presume, due to the slight weakness ofthe internal rectus. Fields unaltered. He can distinguisha light thrown from a small mirror, as in testing field forlight in cataract, up to the periphery of the retina. Histelescopic vision is very curious to watch. He runsagainst things in a most surprising way. He is in remark-ably good healuh, and suffers from nothing except occa-sionally running against lamp-posts. He walks twenty QUININE-AMAUROSIS. 195. The upper chart shows field io* white on April 19th. The lower chartwas taken on December 4th. — • repiesents field for white. » » violet. ,. „ red. » M green. 196 DISEASES OF THE OPTIC NERVE. miles without fatigue, patellar reflexes normal, no sign ofcerebral or spinal mischief. Cases of this description are not common. They havebeen recorded in America and on the Continent, wherequinine is used more freely than with us, both in malariaand pyrexia. The notes for the most part are imperfect,but I have been able to collect reference to eighteen cases,including my own. Graefe, two cases (quoted Med. Times and Gaz., June5th, 1858). 1. Intermittent fever ; 2 to 3 grammes of quinine dailyfor six or eight days, and then smaller doses for failure of vision; no contraction of field butgeneral failure. Second case no details. Galezowski (^ Les Amblyopies Toxiques/p. 148, 1877) ;pernicious fever in Havana. Complete blindness aftertaking 7 grammes; could no


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Keywords: ., bookcentury1800, bookdecade1880, bookpu, booksubjectophthalmology