A text-book of physiology for medical students and physicians . of Experimental Physiology, 1, 121,161, 1908. X Journal of Experimental Medicine, 3, 245, 1898; also Schafer andVincent, Journal of Physiology, 25, 87, 1899; and Herring, QuarterlyJournal of Experimental Physiology, 1, 261, 1908. § Schafer and Herring, Philosophical Transactions, Royal Society,London, 1906, B. cxcix., 1. 864 PHYSIOLOGY OF DIGESTION AND SECRETION. made from the posterior lobe when injected into the blood causea dilatation of the renal vessels and an internal secretion ofurine. Evidence was thus obtained that the po


A text-book of physiology for medical students and physicians . of Experimental Physiology, 1, 121,161, 1908. X Journal of Experimental Medicine, 3, 245, 1898; also Schafer andVincent, Journal of Physiology, 25, 87, 1899; and Herring, QuarterlyJournal of Experimental Physiology, 1, 261, 1908. § Schafer and Herring, Philosophical Transactions, Royal Society,London, 1906, B. cxcix., 1. 864 PHYSIOLOGY OF DIGESTION AND SECRETION. made from the posterior lobe when injected into the blood causea dilatation of the renal vessels and an internal secretion ofurine. Evidence was thus obtained that the posterior lobe fur-nishes an internal secretion which has a specific effect upon theorgans of circulation and upon the kidneys. In addition, it hasbeen shown that these extracts cause dilatation of the pupils andstimulate the musculature of the bladder, uterus, and work by Herring* has made it very probable that thisinternal secretion is furnished by the epithelial cells of the parsintermedia. These cells apparently invade the pars nervosa,. Fig. 299.—Mesial sagittal section through developing pituitary body of a human fetus(fifth month;. Drawing from a photograph. — (Herring.) a, Optic chiasma ; b, tongue-like process of epithelium ; c, third ventricle ; d, anterior lobe ; e, neck of posterior lobe;/, epithelium surrounding neck ; g, epithelial cleft ; li, posterior lobe. undergo a hyaline transformation, and are finally discharged intothe third ventricle of the brain. The active material (pituitin)is formed or activated during the process of transformation in thenervous lobe and it has been possible to prove its presence in thecerebrospinal liquid, f There is some evidence also from histo-logical appearances that this secretion is augmented after completethyroidectomy, a fact which has Led to the view that there is afunctional relationship between this lobe of the pituitary body andthe thyroid tissue. Physiological experiments upon the largeglandular ant


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