. General surgical pathology and therapeutics, in fifty-one lectures .. . sof the cranial bones with bonysubstance is such a commonchange with advancing age, thatit can hardly be considered aspathological, although it reallybelongs under this head. The causes of sclerosis of boneas a primary disease are entirelyobscure; in some cases syphilismay act as a cause, but the osseousformations occurring in this dis-ease rarely attain such firmnessas in sclerosis proper. The mal-ady will rarely be recognized with Sclerosed tibia and femur; the former after , . , -, * -, , Follin, the latter from a
. General surgical pathology and therapeutics, in fifty-one lectures .. . sof the cranial bones with bonysubstance is such a commonchange with advancing age, thatit can hardly be considered aspathological, although it reallybelongs under this head. The causes of sclerosis of boneas a primary disease are entirelyobscure; in some cases syphilismay act as a cause, but the osseousformations occurring in this dis-ease rarely attain such firmnessas in sclerosis proper. The mal-ady will rarely be recognized with Sclerosed tibia and femur; the former after , . , -, * -, , Follin, the latter from a specimen out of the Certainty during lite, because to Vienna Pathological Anatomical Collection. the touch these bones present nothing more than a certain increase of thickness and a slight ine-quality of surface. Ostitis interna suppurativa circumscripta usually begins in ahollow bone as osteomyelitis. The inflammation gradually extendsto the inner surface of the cortical substance, which is dissolved, aswe have already stated, and finally completely consumed at some. 462 CHRONIC INFLAMMATION OF THE PERIOSTEUM, BONE, ETC. point. In such cases pus may form quite early in the centre of theinflammatory new formation, and subsequently be evacuated. It isthis disease that is especially termed bone abscess. The periosteumdoes not remain unaffected; it is thickened and new bony depositsform in this case also from the surface of the bone, which is not atfirst perforated but is irritated from within. The hollow bone is thusenlarged externally at the point where the abscess forms in it, andgives the impression of the bone being here pressed apart and in-flated. It is difficult, indeed often impossible, to distinguish such abone-abscess from a circumscribed osteoplastic periostitis, hence weshould not be in too great haste to operate. This central caries maybe accompanied by partial necrosis of certain portions of bone on theinner surface of the cortical substance, forming a caries necr
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