Diptheria, its nature and treatment . e, consisting offibrinous filaments and granules beset with pus-corpuscles, orof shining homogeneous blocks representing cells which haveundergone coagulative necrosis. This false membrane is con-nected with the underlying structures by fibrinous threads,but is usually loosely adherent and can be readily stripped off,disclosing the reel hyperamiic mucous membrane beneath. 1 Text Book on Pathological Anatomy and Pathogenesis, Section 50 DIPHTHERIA; ITS NATURE AND TREATMENT. The epithelial cells are always more or less injured, being eithernecrotic or
Diptheria, its nature and treatment . e, consisting offibrinous filaments and granules beset with pus-corpuscles, orof shining homogeneous blocks representing cells which haveundergone coagulative necrosis. This false membrane is con-nected with the underlying structures by fibrinous threads,but is usually loosely adherent and can be readily stripped off,disclosing the reel hyperamiic mucous membrane beneath. 1 Text Book on Pathological Anatomy and Pathogenesis, Section 50 DIPHTHERIA; ITS NATURE AND TREATMENT. The epithelial cells are always more or less injured, being eithernecrotic or in process of degeneration and fibrous structure of the inflamed mucous membrane al-ways contains liquid and cellular exudations. Diphtheritic Inflammation.—When a mucous membraneis injured in such a way that its epithelium dies without des-quamation, while its blood-vessels are damaged and pour outan abundant exudation, it sometimes happens that the deadepithelial cells become saturated with the exuded liquid and. e J> e Fig. 6.—Section through the Uvula in Diphtheritis Faucium. (Aniline-brown staining;X 75.) a, normal epithelium; 6, normal areolar tissue; c, necrosed epithelium transformedinto a coarse mesh-work; d, areolar tissue infiltrated with fibrin and leucocytes; e, blood-vessels; /. haemorrhage; g, heaps of micrococci. then pass into a peculiar condition of rigidity akin to coagula-tion. The seat of this change appears to the naked eye as adull grayish raised patch surrounded by red and swollen mucousmembrane. The exudation is rich in albumen and the trans-formed cells take on the appearance of a kind of coarse mesh-work almost or altogether devoid of nuclei. The sub-epithelialareolar tissue is beset with filaments of fibrin and are not uncommon. Inflammations of thiskind, in which the tissue itself coagulates into a solid mass, arecalled diphtheritic. When the necrosis and coagulation extend PATHOLOGY. 51 only to the e
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