. The thyroid gland in health and disease. Fig. 51.—Experimentally-prodiiced atrophy in thyroid of dog ; note completeabsence of colloid except for one inspissated mass, disappearance of alveolarstructure, destruction and desquamation of cells, invasion by fibroblasts andcommencing formation of young fibrous tissue. X Fig. 52.—Normal thyroid gland of dog. Note vesicles lined by single layerof epithelium, abundance of colloid. X 500. These dogs were each given nine 48-hour agar culture tubesfrom which the growths of the intestinal spore-bearing organism, 120 EXPERIMENTAL CONSIDERATIONS wh
. The thyroid gland in health and disease. Fig. 51.—Experimentally-prodiiced atrophy in thyroid of dog ; note completeabsence of colloid except for one inspissated mass, disappearance of alveolarstructure, destruction and desquamation of cells, invasion by fibroblasts andcommencing formation of young fibrous tissue. X Fig. 52.—Normal thyroid gland of dog. Note vesicles lined by single layerof epithelium, abundance of colloid. X 500. These dogs were each given nine 48-hour agar culture tubesfrom which the growths of the intestinal spore-bearing organism, 120 EXPERIMENTAL CONSIDERATIONS which had been obtained from, the faeces of a goitrous horse (seep. 54), were washed. One of these animals developed spasms ofthe limbs, which lasted for six hours and did not recur; a secondwas unaffected; in a third the animal became stiff and unsteady inhis limbs about six hours after he had eaten the the following day he developed pronounced spasms of themuscles of the limbs and tail. He was unable to stand, andwhen propped up his legs gave way under him. These symptomspersisted, the animal lost consciousness, a blood-stained dischargefrom the mouth, nose, and anvis appeared on the fourth day, andhe died on the ninth day of the experiment. The thyroid lobeswere removed with two enlarged lymph
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Keywords: ., bookcentury1900, bookdecade1910, bookpublishernewyorkwilliamwood
