The Journal of nervous and mental disease . f muscle was droppedimmediately after excision into a one-half-per-cent solutionof chromic acid and left there until sufficiently was then transferred into strong alcohol, imbedded incelloidin and cut both transversely and sections thus obtained were then stained, some ofthem in an ammoniacal solution of carmine, and others ina one-half-per-cent solution of chloride of gold. There-upon the specimens were mounted in glycerin. It is wellhere to lay stress upon this fact, as the illustrations in Erbs 142 GEORGE \V. JACOB Y


The Journal of nervous and mental disease . f muscle was droppedimmediately after excision into a one-half-per-cent solutionof chromic acid and left there until sufficiently was then transferred into strong alcohol, imbedded incelloidin and cut both transversely and sections thus obtained were then stained, some ofthem in an ammoniacal solution of carmine, and others ina one-half-per-cent solution of chloride of gold. There-upon the specimens were mounted in glycerin. It is wellhere to lay stress upon this fact, as the illustrations in Erbs 142 GEORGE \V. JACOB Y. monograph, repeatedly referred to above, were taken fromspecimens mounted in Canada balsam, and to this circum-stance I am inclined to attribute the lack of details whichis apparent in those drawings, and which differs so mark-edly from that which I have seen. The appearances inmv own specimens under a comparatively low power(300 were so striking that the necessity of compar-ing them with sections of a normal muscle at once became. Fig. 2.—Myotonia congenita. Quadriceps femoris. Transverse section. X 300. apparent. The piece of muscle used for comparison wasexcised in the same manner, from the same locality, andfrom a healthy man of nearly the same age and size as wasthe diseased piece. It was then also placed at once in a one-half-per-cent solution of chromic acid and, in short, treatedand mounted in the same manneras described above. Con-siderable time and care were necessary in order to obtain asuitable subject from whom to take this piece, but thiswas done purposely, as I feel sure that muscle taken from THOMSENS DISEASE. 143 a corpse would have been considered, and quite justly Iadmit, as worthless for the purposes of comparison and ofdrawing definite conclusions. Transverse sections of theaffected muscles revealed with 300 diam. the following-facts, substantially in agreement with the statements andconclusions of Erb.


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Keywords: ., bookcentury1800, bookdecade1870, booksubjectpsychologypathologic