. Contributions from the Department of Neurology and the Laboratory of Neuropathology (reprints). olumns of Goll, arefindings obtained in the case reported in this paper, and so faras I know, not previously observed. There is need of explanationfor the integrity of sensation when the posterior columns are sogreatly altered. The following notes were taken while_ the patient was in theservice of Dr. Mills and from my observations after the death ofthe patient. She was in my service five days after I came onduty at the hospital. Read at the thirty-sixth annual meeting of the .American Neuro-logic
. Contributions from the Department of Neurology and the Laboratory of Neuropathology (reprints). olumns of Goll, arefindings obtained in the case reported in this paper, and so faras I know, not previously observed. There is need of explanationfor the integrity of sensation when the posterior columns are sogreatly altered. The following notes were taken while_ the patient was in theservice of Dr. Mills and from my observations after the death ofthe patient. She was in my service five days after I came onduty at the hospital. Read at the thirty-sixth annual meeting of the .American Neuro-logical Association, May 2, 3 and 4, 1910. 411 412 WILLIAM G. SPILLER H. AIcC—, laboratorj number 514, female, white, age 24 yrs.;was admitted to the Philadelphia General Hospital, December 19,1909, and died January 5, 1910. Her father died at the age of57 from uremia. Her mother died from insanity. Two brothersare living; one sister died in childhood, and was physically defec-tive. One of the patients near relatives had the same peculiargait that the patient had. A paternal uncle was Fig. I. Spinal cord from a case of Friedreichs ataxia (on the left),(Case I.). (Tompare this with the normal cord on the right. The symptoms were first noticed when the patient was 7 yearsold. She staggered then as though drunk and the staggeringincreased gradually. At the age of 10 she was able to staggeraround and run a little; she could still walk when 12 years ofage, and when 15 years old was able to walk by supporting herself FRIEDREICHS ATAXIA 43 by leaning against objects. She had not been able to walk sinceshe was i8 years of age. She has never had pain, except recentlywhile in the hospital, when she complained of pain below the pupils are equal and regular; the irides react to light and inconvergence. The eyeballs show incoordination in following anobject. Intelligence is not very good. Her speech is defectiveand slow, and articulation is poor. The muscles of the upperl
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