. The elements of pathological histology with special reference to practical methods . he corneal the cicatrisation of larger ulcers there is also in all cases a newformation of blood-vessels (Fig. 207, &), which run to the ulcer fromthe conjunctival limbus. They may again disappear in the subse-quent course of the process, but granular brown pigment is oftenleft behind in the scar. New formation of blood-vessels also takes place, however, shouldthe keratitis become more chronic or frequently recur. The corneamay then eventually become permeated with vessels in its entireextent, the c


. The elements of pathological histology with special reference to practical methods . he corneal the cicatrisation of larger ulcers there is also in all cases a newformation of blood-vessels (Fig. 207, &), which run to the ulcer fromthe conjunctival limbus. They may again disappear in the subse-quent course of the process, but granular brown pigment is oftenleft behind in the scar. New formation of blood-vessels also takes place, however, shouldthe keratitis become more chronic or frequently recur. The corneamay then eventually become permeated with vessels in its entireextent, the condition being spoken of as pannus tenuis or ^:>«72?i?^s CORNEAL ULCER 407 crassus according as the vessels occupy the superficial parts onlyor the deeper parts as well. The vessels run a radiating course,and are always embedded in a connective tissue more or less richin cells. When a corneal ulcer of smaller size perforates into the anteriorchamber, the iris becomes adherent, and forms a permanent attach-ment to the site of the perforation {anterior synechia, Fig. 208, g),. Fig. 208.—Cicatrised Perforation of the Cornea after Suppurative KeratitisAND Prolapse of the Iris, x 50. (Hsematoxylin and eosin.) a, Cornea; h, Cornealepithelium ; c, Part of cornea thrown into folds and infiltrated with cells; d, Prolapsedportion of iris healed into the corneal cicatrix; e, Blood-vessels with sclerotic walls, intransverse section ; /, Haemorrhages in the iris; g, Iris adherent to posterior surface ofcornea (anterior synechia); h, Membrane of Descemet. the tissue of the iris often growing into the corneal cicatrix. If,however, a larger ulcer ruptures, the result is prola,pse of the iris,and here also the prolapsed part (Fig. 208, d), whilst at thesame time becoming atrophic, contracts adhesions to the cornealcicatrix, its fibres merging quite imperceptibly into the tissue ofthe scar. Not only do corneal cicatrices gradually become poorer incells and firmer, but lime-salts or colloid


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Keywords: ., bookcentury1800, bookdecade1890, booksubjectpatholo, bookyear1895