Tropical diseases bulletin . 307 TROPICAL DISEASES BUREAU. TROPICAL DISEASESBULLETIN. Vol. 18.] 1921. [No. 5. BERIBERI : A CRITICAL Surgeon Rear-Admiral Sir P. W. Bassett-Smith, (retd.), , , , Sectional Editor, Tropical Diseases Bureau. No great advance has been made during the past few years in ourknowledge of the etiology, pathology, or treatment of beriberi. Thegeneral consensus of opinion that the disease is only the evidence ofan avitamin syndrome which includes a widely spreading grouphaving rickets at one extremity and beriberi at the other, a
Tropical diseases bulletin . 307 TROPICAL DISEASES BUREAU. TROPICAL DISEASESBULLETIN. Vol. 18.] 1921. [No. 5. BERIBERI : A CRITICAL Surgeon Rear-Admiral Sir P. W. Bassett-Smith, (retd.), , , , Sectional Editor, Tropical Diseases Bureau. No great advance has been made during the past few years in ourknowledge of the etiology, pathology, or treatment of beriberi. Thegeneral consensus of opinion that the disease is only the evidence ofan avitamin syndrome which includes a widely spreading grouphaving rickets at one extremity and beriberi at the other, as wasdescribed by Darlixg in 1915, has received constantly increasing proof. ^. Bone/ lescon aJL epL^^/i^yseslong boijes. Bone lesi-on at JuncCion and carttia§e» Per-tosteaJ €s S^fccu-tinecus^TTJUscuiaT?, suit.•Serous 4j[oinChaemor rha.^es Spongj^ gxtms ^e rve degeneratcon^ Cardtic h^-pertrcphy anddeotneratiod J>roj>sy_ -PaUy_. Chart showing affinities of the food deficiency syndromes [after Darling] (4602) 1500 11/21 Harrow V 308 Beriberi: A Review. [Dec. 15, 1921. Endemic beriberi was ori,t;inally considered to be a disease confinedto the East in rice-eating natives, or to the crews of ships who hadsuffered great privation in protracted voyages. Through the researchesof Stanton, Eraser and Braddon, who proved the etiological im-portance of the various kinds of rice, and of Holst with regard to thedieting of the seamen, the disease has now been placed under controlas far as advice and medical instruction can place it, but year afteryear evidence is obtained of the wide geographical distribution of itsendemic forms. Cases are reported from the Congo region of Africa among manioceaters by van den Branden, from the east of Belgian Congo byWvDOOGHE (J.), and from Madagascar by Clair (F.) ; in Brazil byEraga (C), Lindsav(J.), and Kodrigues (F.). The latter author statedin 1920 that beriberi was st
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