. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. ! JHA-activation ; K+ channel blockage Jttft***** Protein Kinase C (active) f Ca++ channel activation Membrane depolarization; closed open. Figure 8. Model for the juvenile hormone (JH) signal-transduction pathway in Capitella sp. I larvae. In this proposed model, JH induces settlement and metamorphosis by directly interacting with and activating cytosolic protein kinase C (PKC), which acts as the cellular receptor in the larval chemosensory cells. This activation of PKC then causes the closure of potassium channels by phosp
. The Biological bulletin. Biology; Zoology; Biology; Marine Biology. ! JHA-activation ; K+ channel blockage Jttft***** Protein Kinase C (active) f Ca++ channel activation Membrane depolarization; closed open. Figure 8. Model for the juvenile hormone (JH) signal-transduction pathway in Capitella sp. I larvae. In this proposed model, JH induces settlement and metamorphosis by directly interacting with and activating cytosolic protein kinase C (PKC), which acts as the cellular receptor in the larval chemosensory cells. This activation of PKC then causes the closure of potassium channels by phosphorylation. invoking membrane depolarization, and the subsequent opening of voltage-activated calcium channels. PKC and calcium may in subsequent steps activate transcription factors and protein kinases, leading to changes in gene activity, and also cause neurotransmitter release. cellular events that transduce the external JH signal and lead to settlement and metamorphosis. One well-characterized effect of PKC activation is the modulation of ion transport- ers such as a Na+/K+ ATPase (Ilenchuk and Davey. 1987; Sevala and Davey. 1989), Na+/H+ exchangers (Berridge, 1984), and ion channels (Kaczmarek, 1987; Shearman etai,. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Marine Biological Laboratory (Woods Hole, Mass. ); Marine Biological Laboratory (Woods Hole, Mass. ). Annual report 1907/08-1952; Lillie, Frank Rattray, 1870-1947; Moore, Carl Richard, 1892-; Redfield, Alfred Clarence, 1890-1983. Woods Hole, Mass. : Marine Biological Laboratory
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Keywords: ., bookauthorlilliefrankrat, booksubjectbiology, booksubjectzoology
