. The Pharmaceutical era. r the value of a complete file of Eras is sureto be enhanced. We can supply back numbers in bound volumes (PullCloth) at the following prices, which include expresstharges, to any point within the United States. Foreignorders f. o. b. New L, 1887 Vol. IX., , $ Vol. ] Vol. 1II., Vol. IV., 1890 Vol. v., , 3 on Vol. X., July-Dec, 1893 3 00 Vol. XL, , 300 Vol. July-Dec, ..50 , , Vol. VI .July-Dec, 2 50 Vol. XIV., July-Dec, 1895.


. The Pharmaceutical era. r the value of a complete file of Eras is sureto be enhanced. We can supply back numbers in bound volumes (PullCloth) at the following prices, which include expresstharges, to any point within the United States. Foreignorders f. o. b. New L, 1887 Vol. IX., , $ Vol. ] Vol. 1II., Vol. IV., 1890 Vol. v., , 3 on Vol. X., July-Dec, 1893 3 00 Vol. XL, , 300 Vol. July-Dec, ..50 , , Vol. VI .July-Dec, 2 50 Vol. XIV., July-Dec, VII .Jan-June, 1892. 2 50 Vol. XV., Jan-June, VIII., July-Dec. 1892 Vol. XVI., July-Dec, For the convetiience of subscribers who preserve their copies of TheEra, we furnish a use-ful binder which willhold the copies forsix months (1 Vol.),with the advertise-ments, or the textpages only, for an en-tire year. The Era Binder,75 cents per copy,post paid. To foreigncountries, $ THE SUBSTITUTION PROBLEM. A CAREFUL REVIEW OF THE CAUSES WHICH LEDTO PRESENT CONDITIONS—HOW THE EVIL CANBE REMEDIED. At the recent annual meeting of the American Pub-lishers Association held in this city, by special requesta number of the leading proprietors of proprietary medi-cines held a conference with these publishers of the largedaily papers to give particular consideration to the sub-ject of substitution. Nothing was accomplished at thisconference except to refer the matter to a special com-mittee consisting of three publishers and three proprie-tors, who were to suggest means for this in one sense this might have been called a mer-cenary conference, it is by touching ones pocketbookthat you get to his soul, and we believe that the and the drug trade particularly are to bo con-gratulated upon the fact that these two important factorsare sulliciently aroused to give this subject of substitu-tion their special stu


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Keywords: ., bookcentury1800, booksubjectdrugs, booksubjectpharmacy, bookyear1