. A practical treatise on diseases of the skin, for the use of students and practitioners . ch, of Path. Anat., bd. Ixxx., hft. 1.« Ctblt. f. Chir., No. 16, 1874. 374 DISEASES OF THE SKIX. case, which was a sample of the false neuromata of Virchow(fibroid rumors of the nerve), there was no pain throughout thecourse of the disease. The nodules were not arranged along the tracts of nerves;were immovable, dense, and elastic; were fixed in the coriumand extended below it. They were purplish to pinkish in color;and the -kin between them was unaltered, or like that envelop-ing the lesions, dry. unev


. A practical treatise on diseases of the skin, for the use of students and practitioners . ch, of Path. Anat., bd. Ixxx., hft. 1.« Ctblt. f. Chir., No. 16, 1874. 374 DISEASES OF THE SKIX. case, which was a sample of the false neuromata of Virchow(fibroid rumors of the nerve), there was no pain throughout thecourse of the disease. The nodules were not arranged along the tracts of nerves;were immovable, dense, and elastic; were fixed in the coriumand extended below it. They were purplish to pinkish in color;and the -kin between them was unaltered, or like that envelop-ing the lesions, dry. uneven, and desquamative. The tubercleswere both lender and painful, the pain being excruciating,paroxysmal, usually lasting in Duhrings case for an hour, andradiating. It was aggravated by temperature changes, mentalemotion, and movement. Sections of the growth in Duhrings case showed anatomicallya connective tissue stroma, interwoven with fibres for the lying parallel with one another, each fibre composed of afinely granular central substance surrounded by a sheath con-Fig. Painful neuroma of the skin ; external appearance. (Dnhring.) taining numerous, elongated, oval, somewhat granular was also yellow elastic tissue, bloodvessels with thickenedand nucleated walls, and about the latter lymphoid, cell-likebodies. There was entire absence of unstriated muscular andfibrillar connective tissue. The specimen was certainly unique,representing the true amyelinic neuromata of Virchow. InKosinskfs case, non-medullated nerve fibres and connective tissue NEUROMA 375 were also discovered. In both cases, exsection of a portion ofnerve (brachial plexus, of the one; and small sciatic, of the other)was followed by considerable diminution of the pain, and almostentire disappearance of the growths. In Rumps case, which, asstated above, represented the fibromata and so-called tibro-nucle- Fig. 38.


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