. Cellular basis and aetiology of late somatic effects of ionization radiation. Radiation -- Physiological effect. SERIAL TRANSPLANTATION OF HAEMATOPOIETIC TISSUE 61 Serial passage of bone-marrow in irradiated isogenic hosts Two sets of experiments were designed to study the effect of successive transfers upon the activity of bone-marrow. In the first, C3H marrow (2-6 X 106 cells) was serially passaged into five different groups of irradiated. 15 10 Leucocytes/mm R Control ,--o A 7 14 28 xlO^ Control Mononuclears/mm K xlO 10 ft Polymorphs/mm ,/3 O' jy' 7 XT' <2 Control / ^^4 ^1—•- 14 28 7 1
. Cellular basis and aetiology of late somatic effects of ionization radiation. Radiation -- Physiological effect. SERIAL TRANSPLANTATION OF HAEMATOPOIETIC TISSUE 61 Serial passage of bone-marrow in irradiated isogenic hosts Two sets of experiments were designed to study the effect of successive transfers upon the activity of bone-marrow. In the first, C3H marrow (2-6 X 106 cells) was serially passaged into five different groups of irradiated. 15 10 Leucocytes/mm R Control ,--o A 7 14 28 xlO^ Control Mononuclears/mm K xlO 10 ft Polymorphs/mm ,/3 O' jy' 7 XT' <2 Control / ^^4 ^1—•- 14 28 7 14 21 28 Time post-irradiation (days) Fig. 1. Peripheral blood analysis of C3H mice before and after exposure to 650 r total-body irradiation, showing the effect of an injection of 5x 10^ isogenic bone-marrow cells given 24 hours after irradiation. _0_©— Irradiated; — O — O — Irradiated, given Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Harris, R. J. C. (Robert John Cecil), 1922-; Unesco; International Atomic Energy Agency. London, New York, Academic Press
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