. Diseases of the rectum and anus: designed for students and practitioners of medicine. round-celled, small and large spindle-celled, medullary, mela-notic, cysto-, and lympho- sarcomata. In most instances sar-comatous growths of the rectum are of the small, round-celledvariety, though a few cases of spindle-celled sarcomata havebeen reported as occurring in this region. The small-celled sarcoma is usually soft, of more rapid de-velopment, and more malignant than the large-celled rapidity of the growth of these tumors depends principallyupon the vascular supply and the amount of th
. Diseases of the rectum and anus: designed for students and practitioners of medicine. round-celled, small and large spindle-celled, medullary, mela-notic, cysto-, and lympho- sarcomata. In most instances sar-comatous growths of the rectum are of the small, round-celledvariety, though a few cases of spindle-celled sarcomata havebeen reported as occurring in this region. The small-celled sarcoma is usually soft, of more rapid de-velopment, and more malignant than the large-celled rapidity of the growth of these tumors depends principallyupon the vascular supply and the amount of the fibrous-tissueconstituent; when these are abundant, the tumors are of slowgrowth (Plate XXXIV), and, when scanty, growth is more EXPLANATION OF PLATE XXXIII The photograph shows the inner muscTilar coat ofthe rectum infiltrated by round sarcoma-cells, with in-tensely hyperchromatic nuclei and relatively smallamount of protoplasm. The fusiform cells with elon-gated nuclei are the involuntary muscle-fibers, somewhatcompressed and atrophied on account of the infiltration. FLUTE XXXIH. Sarcama of thB REctam, [Magnificatian, 25D.] MALIGNANT TUMORS 523 rapid. When the tumor is poor in connective tissue, it is desig-nated as medullary, and, when it is hard and composed princi-paHy of this tissue, it is designated as scirrJiiLs,^ or hard {sar-coma durum). The latter are usually well-defined tumors. Sarcomatous tumors may ulcerate or undergo fatty, mu-coid, or cheesy degeneration (coagulation necrosis). They areusually single, but in rare cases may be multiple. Sarcomata of the rectum may develop in the subserosa,mucosa, or submucosa; but in the majority of instances theyoriginate in the latter, and may extend into the mucous mem-brane, but more frequently spread outward and deeply intothe perirectal structures. Lymphosarcoma deserves special mention because it is sodifferent in location and structure from the other forms of sar-coma. This variety of sarcoma is characterized by the ma
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Keywords: ., bookcentury1900, bookdecade1910, booksubjectanusdis, bookyear1910
