American journal of physiology . with considerable difficulty,140 gm. of lean meat. Immediate etherization. Stomach con-tained food just ingested. No macroscopic remnants of pancreasfound. The 5 cc. urine found in the bladder did not reduceFehlings solution. The increased amount of food consumed by the animal towards theterminal stages of the disease {as high as gm. meat per kg. bodyweight) cotnpares favorably with a change in character and increasedvigor of the hunger contractions. Polyphagia in Pancreatic Diabetes 317 Dog II. Fox terrier. Jan. 22, 1913: Pancreatectomy withpancreatic gra
American journal of physiology . with considerable difficulty,140 gm. of lean meat. Immediate etherization. Stomach con-tained food just ingested. No macroscopic remnants of pancreasfound. The 5 cc. urine found in the bladder did not reduceFehlings solution. The increased amount of food consumed by the animal towards theterminal stages of the disease {as high as gm. meat per kg. bodyweight) cotnpares favorably with a change in character and increasedvigor of the hunger contractions. Polyphagia in Pancreatic Diabetes 317 Dog II. Fox terrier. Jan. 22, 1913: Pancreatectomy withpancreatic graft according to Hedon.^ From Jan. 29, 1913, on,took daily records of the empty stomach 24 hours after the lastmeal. The types of contraction on the succeeding days were asfollows: Jan. 31, 1913: Types I and II (Fig. 4). Feb. I, 1913: Types I and 11. Feb. 2, 1913: Type III. Feb. 3-Feb. 7 (inclusive): Type III. Feb. 8, 1913: Removal of the subcutaneous pancreatic graftunder hght ether anesthesia. Wet weight of graft: 3 gm. Intense. Dog II. Figure 4. Jan. 31, 1913. Four-fifths the original size. Type II contrac-tions indicating moderate hunger. The horizontal line represents o mm. bromo-form pressure. polyuria and glycosuria followed this operation immediately. (SeeTable II.) Feb. 9-12 (inclusVe): The contractions during this period con-formed to the type described as type III. In spite of the fact thatthe stomach was in a high state of tonus, small tetany periods ofseveral minutes duration were noticed in addition. Feb. 13-15 (inclusive): The contractions were the most pro-nounced (type III) seen in any dog under any condition up to thattime. Figure 5 represents a portion of the tracing taken on Feb- 1 Hedon: Archives Internationales de physiologie, 1911, x, p. 350. 3i8 Arno B. Luckhardt > C! a o hi o e 0) (J H eoo •T3 ni 3(/2 o o o o o o ID lO t^ CO CO U-) o ?* r^ ro CN t—I »-i S ^•~ o O . ro 00 ^—t ^—t lO 00 CO ro ^ t>0O o ^ vO 00 00 OS -i3,bp S ^ bb o ^ 2 o o
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