. The diseases of infancy and childhood. duringthe period of active symptoms. This is usually moderate in swelling of the spleen is chiefly due to simple hyperplasia. Enlarge-ment of the liver is less frequent, and may occur with or without that ofthe spleen. There are no constant changes in the structure of theseorgans. The lymph nodes are frequently enlarged. This is due tosimple hyperplasia, and has no close connection with rickets. Cerebral RICKETS 247 changes are rare, and those described are rather of accidental occurrencethan dependent upon the rachitic process. As stated und
. The diseases of infancy and childhood. duringthe period of active symptoms. This is usually moderate in swelling of the spleen is chiefly due to simple hyperplasia. Enlarge-ment of the liver is less frequent, and may occur with or without that ofthe spleen. There are no constant changes in the structure of theseorgans. The lymph nodes are frequently enlarged. This is due tosimple hyperplasia, and has no close connection with rickets. Cerebral RICKETS 247 changes are rare, and those described are rather of accidental occurrencethan dependent upon the rachitic process. As stated under Symptoms,enlargement of the head is usually due to thickening of the cranial hydrocephalus is occasionally seen, it is extremely doubtfulwhether it is more frequent than in patients not rachitic. Hypertrophyof the brain has been described in connection with rickets, but as yetthis does not seem to be established by sufficient pathological muscles are flabby from imperfect nutrition, and sometimes atrophied. Fio. 20.—Costochondral Junction in Marked Rickets. (A) cartilage, (B) rib, (C)masses of cartilage cells, (D) metaphysis or transitional zone, composed of masses ofcartilage cells, osteoid tissue, blood vessels and fibrous tissue. Normal marrow inthis zone is absent.—Note that the epiphyseal line no longer exists. from disuse, but uo essential anatomical changes have been demonstratedin them. Symptoms.—The symptoms upon which a diagnosis of rickets can bebased are chiefly bony symptoms. Lesions of the bones must exist someweeks before they reach a degree that can be recognized has found microscopical evidences of rickets as early as theend of the second month. In the clinic we seldom see unmistakablerickets before the fourth or fifth month. A well-marked case of ricketsmakes a striking picture (Plate III), and one not easily mistaken. 248 NUTRITION There are seen the large head, beaded ribs, narrow chest, prominent abdo-
Size: 1505px × 1660px
Photo credit: © Reading Room 2020 / Alamy / Afripics
License: Licensed
Model Released: No
Keywords: ., bookcentury1900, bookdecade1920, bookpublishernewyo, bookyear1920
