. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . Fig. 207a.—A whole ovum. Reduced. marked destruction of the tissues, which are beginning to dis-integrate. The top of the head is ulcerated, in front it isnecrotic and pigmented, as is frequently the case in otherembryos. The nervous system shows the usual changes seenin strangulated embryos. The vascular system of the embryois gorged with blood, but none is within the vessels of eitherthe cord or the chorion. Within the body there is quite anextensive migration


. A study of the causes underlying the origin of human monsters : third contribution to the study of the pathology of human embryos . Fig. 207a.—A whole ovum. Reduced. marked destruction of the tissues, which are beginning to dis-integrate. The top of the head is ulcerated, in front it isnecrotic and pigmented, as is frequently the case in otherembryos. The nervous system shows the usual changes seenin strangulated embryos. The vascular system of the embryois gorged with blood, but none is within the vessels of eitherthe cord or the chorion. Within the body there is quite anextensive migration of blood cells into the tissues, obliteratingthem in part, but the process of destruction is not so faradvanced as in No. 205. The majority of the organs can bestill outlined. We have here a rapid infiltration with migrat-ing cells of an embryo of forty days, with cytolysis ratherthan dissociation of the tissues. No. i.] ORIGIN OF HUMAN MONSTERS. 231 The changes in the broken embryo are practically the sameas in the unbroken one, although they are more the head, extremities and cord remain entire, and in. Fig. 207b.—Photograph of the interior of the ovum, showing both em-bryos. Natural size. these the changes are more marked than in the correspondingparts of the unbroken embryo. In the former it is practicallya mass of individual cells, while in the latter the brain isswollen and quite solid. No. 209. Ovum, 20 x 15 x 10 mm.; embryo normal in form, abouttwo and one-half weeks old. Dr. G. N. J. Sommer, Trenton, N. J. The woman from whom the specimen was obtained isthirty years old. Three years ago she had a miscarriageduring the third month of pregnancy, and three months agoshe was delivered of a monster at the end of gestation. Thespecimen was one of hydrocephalus and spina bifida withhydramnios, fully eight liters of fluid coming away at thetime of delivery. She menstruated the first time yesterdaysince her confinement, bleeding profusely all day, and in thee


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