Studies from the laboratories of the Deptof Surgery . estrum has taken place(Figs. 9 to 13). In the second type of ex])eriment. we attempted toproduce osteomyelitis hy inserting, through a hurr holein the humerus, a piece of gauze soaked with bouillonculture of Staf^liylcocciis aureus isolated from a caseof human osteomyelitis, and then transmitted throughdogs and isolated from the blood stream. One of theanimals in which osteomyelitis was produced lived fortwo months with a sinus discharging pus. Hedevclf)ped a cortical sequestrum which was clearlyrevealed by the roentgen ray. Gross section o
Studies from the laboratories of the Deptof Surgery . estrum has taken place(Figs. 9 to 13). In the second type of ex])eriment. we attempted toproduce osteomyelitis hy inserting, through a hurr holein the humerus, a piece of gauze soaked with bouillonculture of Staf^liylcocciis aureus isolated from a caseof human osteomyelitis, and then transmitted throughdogs and isolated from the blood stream. One of theanimals in which osteomyelitis was produced lived fortwo months with a sinus discharging pus. Hedevclf)ped a cortical sequestrum which was clearlyrevealed by the roentgen ray. Gross section of thishumerus showed a cortical se(|uestrum surrounded hyan area of infected granulation tissue, an attemptedwalling off of the medullary canal by new bone pro-liferatirjn, marked rarefaction of the cortex on theopposite side of the shaft, with very marked sub-periosteal bf>ne pnjduction (Figs. 19 to 21). Microscopic sections of the rarefied cortex revealedabsence of nuclei of the cortex, with new subperiostealbone attached to this necrotic Fig. 5.—Sept. 21,1920, capillary tube containing crotoii oil was insertedin medullary canal; roentgenogram taken Oct. 15, 1920, shows larRCsequestrum involving half of humerus: Sq. sequestrum; In. involucrum;,S, separation zone. Figures 5, 6, 7 and 8 are of the same case.
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Keywords: ., bookcentury1900, bookdecade1910, bookpublishernewyork, bookyear19
