. A practical study of malaria. f animals which preyed upon the blood,and that the paroxysms depended upon reproductive acts be-tween which apyrexia occurred. Mitchel, 1849, claimed to have found in the sputa of mala-rial subjects fungous spores in great numbers, which he be-lieved to have been inspired with marsh air and to have causedthe disease. Salisbury, 1866, announced the discovery in the urine andsweat of malarial patients of a species of alga, palmella, com-mon on the marshy regions along the Ohio and MississippiRivers, which he alleged to be the causative element. Until the true para


. A practical study of malaria. f animals which preyed upon the blood,and that the paroxysms depended upon reproductive acts be-tween which apyrexia occurred. Mitchel, 1849, claimed to have found in the sputa of mala-rial subjects fungous spores in great numbers, which he be-lieved to have been inspired with marsh air and to have causedthe disease. Salisbury, 1866, announced the discovery in the urine andsweat of malarial patients of a species of alga, palmella, com-mon on the marshy regions along the Ohio and MississippiRivers, which he alleged to be the causative element. Until the true parasite of malaria was discovered the mostwidely accepted parasitic theory was that proposed in 1879by Klebs and Tommasi-Crudeli. These investigators foundconstantly present in the mud of the Roman marshes a shortbacillus. They were able to cultivate it upon fish gelatine, andwhen injected into rabbits produced a fever similar to named it the bacillus malaria. The malarial parasites were undoubtedly seen and described. Fig. i.—Charles Louis Alphonse Laveran, the discoverer of the parasite of malaria. / INTRODUCTION 21 before Laveran discovered them. In 1847 Meckel, who firstdiscovered malarial pigment, described bodies containing pig-ment which correspond to the malarial parasites. Virchow,in 1849, in a description of the pigment, depicted cells nowknown to be parasites, as did also Frerichs in 1866. The pig-ment was observed also by Dlauhy, Heschl, and Planer. Noneof these investigators, however, recognized the significanceof these bodies, and their parasitic nature was not suspecteduntil 1880 by Laveran, to whom all the more honor is due. Charles Louis Alphonse Laveran was born at Paris, June18, 1845. He entered the military service and was assignedto Algeria, where his brilliant discovery was made on Novem-ber 6, 1880, and announced to the Paris Academy of MedicineNovember 23, 1880. He was using a one-sixth inch dry lenswhen examining the blood. He says,1 My firs


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Keywords: ., bookcentury1900, bookdecade1900, booksubjectmalaria, bookyear1909