The Action of Nicotine and other Pyridine Bases upon Muscle . O p O CDP* COO oo UP -1-3 o +?3 -i p o ° 9 rP PCD o p ^o <» r—< <—* O CN rO O <| © P O • i—t -I— o +3 0-1 ou Po CO OO p P o o13 p gP CD P • i— is Pr 338 Drs. V. H. Veley and A. D. Waller. Action of [Feb. 22: A comparative experiment in which ^/20 and w/40 solutions of pyridineand picoline were alternately applied several times to the same muscle,showed that there was no appreciable difference between the toxic effect ofthese two bases. We assign the following order of molecular toxicity to these bases, = 10
The Action of Nicotine and other Pyridine Bases upon Muscle . O p O CDP* COO oo UP -1-3 o +?3 -i p o ° 9 rP PCD o p ^o <» r—< <—* O CN rO O <| © P O • i—t -I— o +3 0-1 ou Po CO OO p P o o13 p gP CD P • i— is Pr 338 Drs. V. H. Veley and A. D. Waller. Action of [Feb. 22: A comparative experiment in which ^/20 and w/40 solutions of pyridineand picoline were alternately applied several times to the same muscle,showed that there was no appreciable difference between the toxic effect ofthese two bases. We assign the following order of molecular toxicity to these bases, = 100, piperidine = 50, pyridine = 10, picoline = 10. The toxicity of nicotine as compared with that of some other of the poisonsthat we have examined during the past year can be appreciated from thefollowing numbers, which denote relative molecular toxicity as estimated byexperiments on the sartorius muscle :— Aconitine 1000 Quinine 100 Nicotine 33 Theobromine 18 Caffeine 12 Chloroform 6 Ether 0*72
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Keywords: ., bookauthorveleyv, bookcentury1900, bookdecade1910, bookyear1910
