. Carotenoids, their comparative biochemistry. Carotenoids. CAROTENOIDS SO quickly diluted that the resulting small increase in the blood level could not be detected (see Fig. 33).. Hours after dosing Fig. 33.—Showing the rise in the vitamin A in the thoracic lymph of goats after feeding carotene, (from Goodwin, T. W., and Gregory, R. A. {i948) 43, 505.) Krause and Pierce"*^ have demonstrated the intestinal conversion of carotene into vitamin A in rats in which the liver was tied off at the portal vein. In retrospect the explanation of Popper's®^ observation that vitamin A fluorescence so
. Carotenoids, their comparative biochemistry. Carotenoids. CAROTENOIDS SO quickly diluted that the resulting small increase in the blood level could not be detected (see Fig. 33).. Hours after dosing Fig. 33.—Showing the rise in the vitamin A in the thoracic lymph of goats after feeding carotene, (from Goodwin, T. W., and Gregory, R. A. {i948) 43, 505.) Krause and Pierce"*^ have demonstrated the intestinal conversion of carotene into vitamin A in rats in which the liver was tied off at the portal vein. In retrospect the explanation of Popper's®^ observation that vitamin A fluorescence sometimes appeared in the intestine before the liver after the oral administration of carotene is now obvious. Since these first investigations, many confirmatory reports have been published. Using the same technique as that employed by Goodwin and Gregory, ^' Kon and his associates »». i o o ^nd Alexander and Goodwin^^^ have confirmed the intestinal conversion in the rat. Other animals in which this conversion have been demonstrated are chicks,8»' sheep»»• 100 and dairy cattle^o^,io4 Patel, Mehl and Deuel^os j^^ve also demonstrated the conversion of cryptoxanthin into vitamin A in the intestinal wall of the chick, 278. Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Goodwin, T. W. (Trevor Walworth). New York, Chemical Pub. Co.
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