. Diet as a factor in length of life and in structure and composition of tissues of the rat with aging. Table —Maximum age of rats before weight loss in relation to caloric intake during the first 300 days on SP 8 HVO and SPE diets Rats Average healthy lifespan Intake during— Diet and age of rats (days) 0-12 weeks 100-199 days 200-299 days Average Range Average Range Average Range SP8HV0: Less than 500 _ 500 to 599 . Number 15 12 11 6 20 11 6 Days 387 541 624 757 330 423 533 Calories 6, 110 6,000 5,870 5,590 6, 180 6,330 5,610 Calories 5, 260-6, 860 5, 220-6, 960 4, 840-6, 720 5, 030-5, 92
. Diet as a factor in length of life and in structure and composition of tissues of the rat with aging. Table —Maximum age of rats before weight loss in relation to caloric intake during the first 300 days on SP 8 HVO and SPE diets Rats Average healthy lifespan Intake during— Diet and age of rats (days) 0-12 weeks 100-199 days 200-299 days Average Range Average Range Average Range SP8HV0: Less than 500 _ 500 to 599 . Number 15 12 11 6 20 11 6 Days 387 541 624 757 330 423 533 Calories 6, 110 6,000 5,870 5,590 6, 180 6,330 5,610 Calories 5, 260-6, 860 5, 220-6, 960 4, 840-6, 720 5, 030-5, 920 5, 540-7, 120 5, 690-6, 820 5, 020-6, 340 Calories 8, 320 8, 170 7,760 7,890 8,260 7, 940 6,830 Calories 7, 190- 9, 780 7, 280-10, 060 6, 160- 8, 930 6, 670- 8, 410 6, 760-10, 180 6, 170- 9, 140 5, 500- 8, 100 Calories 8,510 8,220 7, 900 7,450 8,610 8,210 6, 950 Calories 7, 100- 9, 870 7, 280- 9, 780 600 to 699 _ 6, 530- 9, 020 700 and over SPE: Less than 400. _ 400 to .. .. 6, 720- 7, 990 7, 060- 9, 290 6, 690-10, 180 500 and over. 5, 570- 7, 730 DIET: SP 8 HVO DIET: SPE GRAMS" 800. .A' v. A' „A-A- - - - ^-^ - - / .& J, A V ' / 'A' - j If — _A -o Obese rats (423 days*) — A- -a Long-lived 1 rats (623 day 1 s* Obese rats (553 days*) ~ a—a Long-lived rats (812 days* I I I U 0 150 300 450 600 0 150 300 450 600 DAYS DAYS * AVERAGE ACE AT DEATH Figure 6.—Comparison of growth curves of obese rats fed SP 8 HVO and SPE diets with those of long-lived rats fed the same diets. diets are all for rats weighing 600 grams or more by 200 days. Of the 18 rapidly growing rats fed these three diets, 8 were dead before reaching 400 days of age; only 1 survived 600 days (603 days on SPB diet). The rats that were still maintaining their weight at 600 days of age grew slowly on all three diets and survived approxi- mately 300 days longer than did the rapidly growing rats fed the corresponding diet. The slowly growing rats tended to reach maximum weights comparable to t
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Keywords: ., bookcentury1900, bookpubli, booksubjectdiet, booksubjectnutrition
