General and dental pathology with special reference to etiology and pathologic anatomy; a treatise for students and practitioners . Inflammation is a factorwhen mucoid degeneration appears in mucous membranes. Locations.—(a) Mucous membrane, affecting the columnar cells,resulting in the formation of a large number of goblet cells, (b)Intercellular substance of subcutaneous, subserous and submucous Wells, II. Gideon, Chemical Pathology, Philadelphia, W. B. Saunders Co. PATHOLOGIC PROC] SSES 51 tissues, either as a diffuse process (myxedema), or as a localprocess in nasal polyps, hydat ilorm mol
General and dental pathology with special reference to etiology and pathologic anatomy; a treatise for students and practitioners . Inflammation is a factorwhen mucoid degeneration appears in mucous membranes. Locations.—(a) Mucous membrane, affecting the columnar cells,resulting in the formation of a large number of goblet cells, (b)Intercellular substance of subcutaneous, subserous and submucous Wells, II. Gideon, Chemical Pathology, Philadelphia, W. B. Saunders Co. PATHOLOGIC PROC] SSES 51 tissues, either as a diffuse process (myxedema), or as a localprocess in nasal polyps, hydat ilorm moles, etc. (c) In tumors, asovarian cysts, carcinoma springing from mucous membranes (theso-called colloid cancers), myxomata, etc. Gross Morbid Anatomy.—The mucous membranes are coveredwith a viscid semigelatinous and colorless material, while in theantrum of Highmore, salivary glands, etc., there are cyst-like col-lections of the same material. When affecting the connectivetissues, these are soft, elastic and tear easily. In tumors themucoid material is drier; in ovarian cysts the material may as-sume large > Fig. 6.—Mucoid degeneration of fibrous tissue. (Delafield and Prudden.) Minute Morbid Anatomy.—The cells are partly or completelyfilled with the mucus: the typical goblet cells are distendedand the nucleus pressed to one side. The material is usuallyhomogeneous, but in connective tissues it may appear as granulesor as coarse shreds lying between the cells; the cells present allstages of degeneration from the normal appearance to typicalmucoid cells, with irregularly stellate outline. Pathologic Chemistry.—Mucin is a compound protein (gluco-samine normally secreted by the epithelium of mucous mem-branes, and also occurring in the mucoid tissue of the fetus,where it is the precursor of the adult connective tissue. Themucoid degeneration associated with inflammation of mucousmembranes (catarrhal inflammation) is in reality only a path- 52 GENERAL PA
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