. Endocrinology. kull—large thin calvarium; skull base steep;sphenoidal angle 151 degrees. Sella small and open. X-ray Plate of Hand—bones delicate in structure—terminal pha-langes show no evidence of tufting. Mental Age (Binet-Simon) : 15 years, no retardation. 236 ABSENCE OF PROSTATE AND ENDOCRTNES Case No. 4 (See Figure 3). U. C. O. P. D. No. 66862, boy, aged15 years. Infantilism ReHembling Levi-Lorain Type of Hypopitui-tarism. Prostate very s)naU. History: The family history was essentially negative except fora sister, aged 17, who had secondary sex characters, but was quiteshort and fat a


. Endocrinology. kull—large thin calvarium; skull base steep;sphenoidal angle 151 degrees. Sella small and open. X-ray Plate of Hand—bones delicate in structure—terminal pha-langes show no evidence of tufting. Mental Age (Binet-Simon) : 15 years, no retardation. 236 ABSENCE OF PROSTATE AND ENDOCRTNES Case No. 4 (See Figure 3). U. C. O. P. D. No. 66862, boy, aged15 years. Infantilism ReHembling Levi-Lorain Type of Hypopitui-tarism. Prostate very s)naU. History: The family history was essentially negative except fora sister, aged 17, who had secondary sex characters, but was quiteshort and fat and mentally aged about 3. The past history revealedmeasles, mumps; tonsils and adenoids removed. The patient felt well—noticed that he had not grown for two years. Examination showed him to be undersized, underdeveloped, slen-der. His height was 4 feet 6% inches; weight, 651,^ pounds. He ap-peared physically to be about eight years old; genitalis infantile; nosecondary sex characters; prostate very Fifjiire J, (Coxr :,). ir, years. l,nrain tvpr of infantilism—skeletal under-growth; no prostate felt. Blood Pressure: 110/75. Mental Age was 9 years, or six years retardation; high grade de-fective. The laboratory findings follow. Urine: Negative. Blood Picture: Normal. V. Pirquet: Positive. Blood Wasse7-mann: Negative. Spinal Fluid: Negative. Urine sugar curve: Negative. Blood sugar curve: , , LISSEK 237 X-ray: Plates of Handa negative. Plate of Skull: Short skullbase, small sella, diffuse convolutional markings. Sphenoidal angle11) degrees. Case No. 5 (See Figure 4). U. C. O. P. D. 380079, W. C, years. Preadolcscent HypointnitartHui (Levi-Lorain Infantilism)with Absence of the Prostate. History: Fathers family small; mothers family normal. Onebrother aged 11; four years younger than patient, is larger and taller;one sister aged 7 is normal; one brother aged .i is normal. Full term,bottle fed, birth weight 8 pounds; walked at 1 year.


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Keywords: ., bookcentury1900, bookdecade1910, booksubjectendocrinology, bookye