A reference handbook of the medical sciences, embracing the entire range of scientific and practical medicine and allied science . , we feel,to insufficient and half-hearted therapy. Cerebralsyphilis is usually accompanied by spirochetes, andthe object is to poison them as rapidly as can be done by arsenic, by mercury, and bythe iodides, but these remedies have a very defi-nite variation in their spirochetal toxic is the most active, mercurj next, while action of the iodides, although positive, is veryslight. The treatment of cerebral sjphihs should b


A reference handbook of the medical sciences, embracing the entire range of scientific and practical medicine and allied science . , we feel,to insufficient and half-hearted therapy. Cerebralsyphilis is usually accompanied by spirochetes, andthe object is to poison them as rapidly as can be done by arsenic, by mercury, and bythe iodides, but these remedies have a very defi-nite variation in their spirochetal toxic is the most active, mercurj next, while action of the iodides, although positive, is veryslight. The treatment of cerebral sjphihs should bemost energetic, because smaU lesions may involvevery important areas and result in great deprivationto the patient. The nervous and mental structures 429 Brain, Syphilis of REFERENCE HANDBOOK OF THE MEDICAL SCIENXES are of the greatest importance to the individual in hisstruggle for existence, therefore, syphilis of the brainis alwaj-s an extremely dangerous disease. A com-plete sterilization is desirable, but this is often diffi-cult to bring about, especially in nervous tissues, forreasons as yet not competely Fig. 1079.—Cerebral Sj-philis, Paretic Tj-pe. As has been said, cerebral syphilis may present apositive cerebral spinal fluid Wassermann without apositive blood Wassermann, Hence, a negative Was-sermann should not deter one if the diagnosis is fairlywell established. In fact, an active antisyphilitictreatment, as, for instance, by salvarsan, may sud-denly bring about a change in the Wassermann re-action, showing that latent spirochetes have beenstirred up. Years J » J e~0 £> lUrm ,-3i-S r6f7?TffJS^X^^/a2eJ^^KfK:.\\.y^yJKV^33^JSJeJ7J£ fl Fig. lOSO.—Length of Time after Infection of Appearance ofClinical Signs of Paresis. (Kraepelin.) Space is not available for a complete discussion ofthe treatment of cerebral syphihs, but it would seemthat the trend of modern opinion is to attack it veryactively. The attack, however, should be begun witha certain


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