. Colchicine in agriculture, medicine, biology, and chemistry. Colchicine; Colchicine. Fig. —Stages of restitution in exploded metaphases in the regenerating liver of rats injected with colchicine. Feulgen-fast green staining. A. Eight hours after colchicine. Typical exploded metaphase, without spindle. Scattered and shortened chromosomes. B. Sixteen hours. Chromosome agglutination and lengthening. C. Sixteen hours. Some sug- gestion of catachromatic changes. D. Thirty hours. Formation of large micronuclei; these originate by the catachromatic changes of agglutinated groups of chromosomes.

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. Colchicine in agriculture, medicine, biology, and chemistry. Colchicine; Colchicine. Fig. —Stages of restitution in exploded metaphases in the regenerating liver of rats injected with colchicine. Feulgen-fast green staining. A. Eight hours after colchicine. Typical exploded metaphase, without spindle. Scattered and shortened chromosomes. B. Sixteen hours. Chromosome agglutination and lengthening. C. Sixteen hours. Some sug- gestion of catachromatic changes. D. Thirty hours. Formation of large micronuclei; these originate by the catachromatic changes of agglutinated groups of chromosomes. (Original photomicrographs. Courtesy of A. M. Brues, Univ. of Chicago). Please note that these images are extracted from scanned page images that may have been digitally enhanced for readability - coloration and appearance of these illustrations may not perfectly resemble the original Eigsti, O. J. (Orie Jacob), 1908-; Dustin, Pierre. Ames, Iowa State College Press

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